ET-28 COMBINATION THERAPY WITH MET TYROSINE KINASE INHIBITOR EMD1214063 AND BEVACIZUMAB

od Keir, Stephen, Roskoski, Martin, Gasinski, Danuta, Friedman, Henry, Bigner, Darell
Wydane 2014

LGG-01. EVALUATION OF COBIMETINIB, A MEK INHIBITOR, IN LOW-GRADE PEDIATRIC BRAIN TUMORS

od Roskoski, Martin, Gasinski, Danuta, Friedman, Henry, Bigner, Darell, Keir, Stephen
Wydane w Neuro Oncol (2018)

EGFR and EGFRvIII interact with PUMA to inhibit mitochondrial translocalization of PUMA and PUMA-mediated apoptosis independent of EGFR kinase activity

od Zhu, Hu, Cao, Xinyu, Ali-Osman, Francis, Keir, Stephen, Lo, Hui-Wen
Wydane 2010

[(177)Lu]-DOTA(0)-Tyr(3)-octreotate: A Potential Targeted Radiotherapeutic for the Treatment of Medulloblastoma

od Vaidyanathan, Ganesan, Affleck, Donna J., Zhao, Xiao-Guang, Keir, Stephen T., Zalutsky, Michael R.
Wydane 2010

Proteasome inhibition with bortezomib induces cell death in GBM stem-like cells and temozolomide-resistant glioma cell lines, but stimulates GBM stem-like cells’ VEGF production an...

od Bota, Daniela A., Alexandru, Daniela, Keir, Stephen T., Bigner, Darell, Vredenburgh, James, Friedman, Henry S.
Wydane w J Neurosurg (2013)

Cellular Redox Modulator, ortho Mn(III) meso-tetrakis(N-n-Hexylpyridinium-2-yl)porphyrin, MnTnHex-2-PyP(5+) in the Treatment of Brain Tumors

od Keir, Stephen T., Dewhirst, Mark W., Kirkpatrick, John P., Bigner, Darell D., Batinic-Haberle, Ines
Wydane 2011

Dynamic treatment effect (DTE) curves reveal the mode of action for standard and experimental cancer therapies

od Choudhury, Kingshuk Roy, Keir, Stephen T., Ashcraft, Kathleen A., Boss, Mary-Keara, Dewhirst, Mark W.
Wydane w Oncotarget (2015)

Phosphorylation of Glutathione S-Transferase P1 (GSTP1) by Epidermal Growth Factor Receptor (EGFR) Promotes Formation of the GSTP1-c-Jun N-terminal kinase (JNK) Complex and Suppres...

od Okamura, Tatsunori, Antoun, Gamil, Keir, Stephen T., Friedman, Henry, Bigner, Darell D., Ali-Osman, Francis
Wydane w J Biol Chem (2015)

TMOD-33. ESTABLISHMENT AND PRELIMINARY EVALUATION OF BEVACIZUMAB-RESISTANT GLIOMA XENOGRAFT MODELS

od Keir, Stephen, Waitkus, Matthew, Roskoski, Martin, Friedman, Henry, Bigner, Darell, Yan, Hai, Ashley, David
Wydane w Neuro Oncol (2018)

Initial Testing of VNP40101M (Cloretazine(®)) by the Pediatric Preclinical Testing Program

od Keir, Stephen T., Morton, Christopher L., Billups, Catherine, Smith, Malcolm A., Houghton, Peter J., Gururangan, Sridharan
Wydane 2008

IDENTIFICATION AND PRELIMINARY TREATMENT DATA OF XENOGRAFTS REPRESENTING TCGA-DEFINED SUBTYPES

od Keir, Stephen T., Roskoski, Martin A., Gasinski, Danuta, Kwatra, Madan K., Friedman, Henry S., Bigner, Darell D.
Wydane 2014

Initial Testing of the Multitargeted Kinase Inhibitor Pazopanib by the Pediatric Preclinical Testing Program

od Keir, Stephen T., Morton, Christopher L., Wu, Jianrong, Kurmasheva, Raushan T., Houghton, Peter J., Smith, Malcolm A.
Wydane w Pediatr Blood Cancer (2011)

PATIENT-DERIVED XENOGRAFTS MIRROR THE PROTEOMIC PROFILE OF HUMAN GLIOBLASTOMA: IMPLICATIONS FOR PERSONALIZED DRUG DEVELOPMENT

od Kwatra, Madan M., Brown, Kristine E., Chagoya, Gustavo, Keir, Stephen T., Bigner, Darell D., Sampson, John H.
Wydane 2014

Affinity-matured anti-glycoprotein NMB recombinant immunotoxins targeting malignant gliomas and melanomas

od Kuan, Chien-Tsun, Wakiya, Kenji, Keir, Stephen T., Li, Jianjun, Herndon, James E., Pastan, Ira, Bigner, Darell D.
Wydane 2010

TMOD-27. EFFICACY OF SOLUBLE PANOBINOSTAT (MTX110) IN PRECLINICAL MODELS OF ADULT GLIOBLASTOMA

od Ashley, David, Keir, Stephen T, Roskoski, Martin A, Davies, Rhian, Williams, Ben, Damment, Stephen J P, Conlon, Kelly
Wydane w Neuro Oncol (2020)

Synergistic antitumor effects of 9.2.27-PE38KDEL and ABT-737 in primary and metastatic brain tumors

od Yu, Xin, Dobrikov, Mikhail, Keir, Stephen T., Gromeier, Matthias, Pastan, Ira H., Reisfeld, Ralph, Bigner, Darell D., Chandramohan, Vidyalakshmi
Wydane w PLoS One (2019)

Activity of VNP40101M (Cloretazine) in the treatment of CNS tumor xenografts in athymic mice

od Badruddoja, Michael A., Keir, Stephen T., King, Ivan, Zeidner, Joseph, Vredenburgh, James J., Muhlbaier, Lawrence H., Bigner, Darell D., Friedman, Henry S.
Wydane 2007

Antitumor efficacy of D2C7-(scdsFv)-PE38KDEL, a novel immunotoxin targeting EGFRwt and EGFRvIII, by convection-enhanced delivery in orthotopic brain tumor mouse models

od Bao, Xuhui, Chandramohan, Vidyalakshmi, Keir, Stephen T, Pegram, Charles N, McLendon, Roger E, Kuan, Chien-Tsun, Pastan, Ira H, Bigner, Darell D
Wydane 2013

Recombinant anti-podoplanin (NZ-1) immunotoxin for the treatment of malignant brain tumors

od Chandramohan, Vidyalakshmi, Bao, Xuhui, Kaneko, Mika Kato, Kato, Yukinari, Keir, Stephen T., Szafranski, Scott E., Kuan, Chien-Tsun, Pastan, Ira H., Bigner, Darell D.
Wydane 2012

Affinity-matured recombinant immunotoxin targeting gangliosides 3′-isoLM1 and 3′,6'-isoLD1 on malignant gliomas

od Piao, Hailan, Kuan, Chien-Tsun, Chandramohan, Vidya, Keir, Stephen T, Pegram, Charles N, Bao, Xuhui, Månsson, Jan-Eric, Pastan, Ira H, Bigner, Darell D
Wydane 2013