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Initial Testing of VNP40101M (Cloretazine(®)) by the Pediatric Preclinical Testing Program
VNP40101M is a novel alkylating agent that yields two reactive compounds (a chloroethylating species and methylisocyanate) and has demonstrated activity against a wide spectrum of tumor xenografts. VNP40101M was tested against an in vivo panel of 5 pediatric brain tumor xenografts at a dose of 18 mg...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2836208/ https://ncbi.nlm.nih.gov/pubmed/18493996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.21620 |
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