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ET-28 COMBINATION THERAPY WITH MET TYROSINE KINASE INHIBITOR EMD1214063 AND BEVACIZUMAB
INTRODUCTION: EMD1214063 is a MET tyrosine kinase inhibitor with the potential for antineoplastic activity. Selectively binding to MET tyrosine kinase, EMD1214063 disrupts MET signal transduction pathways which may induce apoptosis in tumor cells overexpressing this kinase. The receptor tyrosine kin...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4218124/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou255.28 |
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