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ET-28 COMBINATION THERAPY WITH MET TYROSINE KINASE INHIBITOR EMD1214063 AND BEVACIZUMAB

INTRODUCTION: EMD1214063 is a MET tyrosine kinase inhibitor with the potential for antineoplastic activity. Selectively binding to MET tyrosine kinase, EMD1214063 disrupts MET signal transduction pathways which may induce apoptosis in tumor cells overexpressing this kinase. The receptor tyrosine kin...

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Detalhes bibliográficos
Main Authors: Keir, Stephen, Roskoski, Martin, Gasinski, Danuta, Friedman, Henry, Bigner, Darell
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218124/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou255.28
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