TMOD-33. ESTABLISHMENT AND PRELIMINARY EVALUATION OF BEVACIZUMAB-RESISTANT GLIOMA XENOGRAFT MODELS

High-grade gliomas characteristically exhibit aberrant neovascularization which is thought to play an important role in GBM progression. One of the main drivers of angiogenesis in GBM is vascular endothelial growth factor A (VEGF-A), which binds to VEGF receptors on endothelial cells and stimulates...

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Dettagli Bibliografici
Pubblicato in:Neuro Oncol
Autori principali: Keir, Stephen, Waitkus, Matthew, Roskoski, Martin, Friedman, Henry, Bigner, Darell, Yan, Hai, Ashley, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2018
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Abstracts
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216685/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.1145
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