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TMOD-33. ESTABLISHMENT AND PRELIMINARY EVALUATION OF BEVACIZUMAB-RESISTANT GLIOMA XENOGRAFT MODELS

High-grade gliomas characteristically exhibit aberrant neovascularization which is thought to play an important role in GBM progression. One of the main drivers of angiogenesis in GBM is vascular endothelial growth factor A (VEGF-A), which binds to VEGF receptors on endothelial cells and stimulates...

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Detalles Bibliográficos
Publicado en:Neuro Oncol
Main Authors: Keir, Stephen, Waitkus, Matthew, Roskoski, Martin, Friedman, Henry, Bigner, Darell, Yan, Hai, Ashley, David
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216685/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.1145
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