ET-28 COMBINATION THERAPY WITH MET TYROSINE KINASE INHIBITOR EMD1214063 AND BEVACIZUMAB

INTRODUCTION: EMD1214063 is a MET tyrosine kinase inhibitor with the potential for antineoplastic activity. Selectively binding to MET tyrosine kinase, EMD1214063 disrupts MET signal transduction pathways which may induce apoptosis in tumor cells overexpressing this kinase. The receptor tyrosine kin...

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Autores principales: Keir, Stephen, Roskoski, Martin, Gasinski, Danuta, Friedman, Henry, Bigner, Darell
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2014
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Abstracts
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218124/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou255.28
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