Recombinant anti-podoplanin (NZ-1) immunotoxin for the treatment of malignant brain tumors

Current study demonstrates the glioma tumor antigen podoplanin to be present at very high levels (>90%) in both glioblastoma (D2159MG, D08-0308MG, and D08-0493MG) and medulloblastoma (D283MED, D425MED, and DAOY) xenografts and cell line. We constructed a novel recombinant single-chain antibody va...

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Autors principals: Chandramohan, Vidyalakshmi, Bao, Xuhui, Kaneko, Mika Kato, Kato, Yukinari, Keir, Stephen T., Szafranski, Scott E., Kuan, Chien-Tsun, Pastan, Ira H., Bigner, Darell D.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3809846/
https://ncbi.nlm.nih.gov/pubmed/23115013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.27919
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