Evaluation of anti-podoplanin rat monoclonal antibody NZ-1 for targeting malignant gliomas

INTRODUCTION: Podoplanin/Aggrus is a mucin-like sialoglycoprotein that is highly expressed in malignant gliomas. Podoplanin has been reported to be a novel marker to enrich tumor-initiating cells, which are thought to resist conventional therapies and to be responsible for cancer relapse. The purpos...

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Main Authors: Kato, Yukinari, Vaidyanathan, Ganesan, Kaneko, Mika Kato, Mishima, Kazuhiko, Srivastava, Nidhi, Chandramohan, Vidyalakshmi, Pegram, Charles, Keir, Stephen T., Kuan, Chien-Tsun, Bigner, Darell D., Zalutsky, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946889/
https://ncbi.nlm.nih.gov/pubmed/20870153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2010.03.010
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