Initial Testing (Stage 1) of Temozolomide by the Pediatric Preclinical Testing Program

BACKGROUND: The DNA methylating agent temozolomide was developed primarily for treatment of glioblastoma. However, preclinical data have suggested a broader application for treatment of childhood cancer. Temozolomide was tested against the PPTP solid tumor and ALL models. PROCEDURES: Temozolomide wa...

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Pubblicato in:Pediatr Blood Cancer
Autori principali: Keir, Stephen T., Maris, John M., Reynolds, C. Patrick, Kang, Min H., Kolb, E. Anders, Gorlick, Richard, Lock, Richard, Carol, Hernan, Morton, Christopher L., Wu, Jianrong, Kurmasheva, Raushan T., Houghton, Peter J., Smith, Malcolm A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244112/
https://ncbi.nlm.nih.gov/pubmed/23335050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.24368
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