Initial Testing (Stage 1) of Temozolomide by the Pediatric Preclinical Testing Program

BACKGROUND: The DNA methylating agent temozolomide was developed primarily for treatment of glioblastoma. However, preclinical data have suggested a broader application for treatment of childhood cancer. Temozolomide was tested against the PPTP solid tumor and ALL models. PROCEDURES: Temozolomide wa...

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Detalhes bibliográficos
Publicado no:Pediatr Blood Cancer
Main Authors: Keir, Stephen T., Maris, John M., Reynolds, C. Patrick, Kang, Min H., Kolb, E. Anders, Gorlick, Richard, Lock, Richard, Carol, Hernan, Morton, Christopher L., Wu, Jianrong, Kurmasheva, Raushan T., Houghton, Peter J., Smith, Malcolm A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244112/
https://ncbi.nlm.nih.gov/pubmed/23335050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.24368
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