Efficacy of CPX-351, (cytarabine:daunorubicin) liposome injection, against acute lymphoblastic leukemia (ALL) xenograft models of the Pediatric Preclinical Testing Program

BACKGROUND: CPX-351, a liposomal formulation of cytarabine and daunorubicin co-encapsulated at an optimized synergistic 5:1 molar ratio, has demonstrated improved clinical outcomes over conventional cytarabine/daunorubicin treatment in a randomized phase 2 trial in patients with AML as well as super...

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Detalhes bibliográficos
Publicado no:Pediatr Blood Cancer
Main Authors: Carol, Hernan, Fan, Mannie M. Y., Harasym, Troy O., Boehm, Ingrid, Mayer, Lawrence D., Houghton, Peter, Smith, Malcolm, Lock, Richard B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237711/
https://ncbi.nlm.nih.gov/pubmed/25203866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.25133
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