Exploiting Necroptosis for Therapy of Acute Lymphoblastic Leukemia

Tekijä Mezzatesta, Caterina, Bornhauser, Beat C.
Julkaisussa Front Cell Dev Biol (2019)

Tissue Expression and Actin Binding of a Novel N-Terminal Utrophin Isoform

Tekijä Zuellig, Richard A., Bornhauser, Beat C., Amstutz, Ralf, Constantin, Bruno, Schaub, Marcus C.
Julkaistu 2011

Rapid Generation of Leukemogenic Chromosomal Translocations in Vivo Using CRISPR/Cas9

Tekijä Huang, Yun, Marovca, Blerim, Dettwiler, Susanne, Bode, Peter Karl, Bornhauser, Beat, Bourquin, Jean-Pierre
Julkaisussa Hemasphere (2020)

PDGF regulates the actin cytoskeleton through hnRNP-K-mediated activation of the ubiquitin E(3)-ligase MIR

Tekijä Nagano, Kohji, Bornhauser, Beat C, Warnasuriya, Gayathri, Entwistle, Alan, Cramer, Rainer, Lindholm, Dan, Naaby-Hansen, Soren
Julkaistu 2006

Venetoclax and Bortezomib in Relapsed/Refractory Early T-Cell Precursor Acute Lymphoblastic Leukemia

Tekijä La Starza, Roberta, Cambò, Benedetta, Pierini, Antonio, Bornhauser, Beat, Montanaro, Anna, Bourquin, Jean-Pierre, Mecucci, Cristina, Roti, Giovanni
Julkaisussa JCO Precis Oncol (2019)

Efficient apoptosis requires feedback amplification of upstream apoptotic signals by effector caspase-3 or -7

Tekijä McComb, Scott, Chan, Pik Ki, Guinot, Anna, Hartmannsdottir, Holmfridur, Jenni, Silvia, Dobay, Maria Pamela, Bourquin, Jean-Pierre, Bornhauser, Beat C.
Julkaisussa Sci Adv (2019)

Fibroblast Growth Factor-21 (FGF21) Regulates Low-density Lipoprotein Receptor (LDLR) Levels in Cells via the E3-ubiquitin Ligase Mylip/Idol and the Canopy2 (Cnpy2)/Mylip-interacti...

Tekijä Do, Hai Thi, Tselykh, Timofey V., Mäkelä, Johanna, Ho, Tho Huu, Olkkonen, Vesa M., Bornhauser, Beat C., Korhonen, Laura, Zelcer, Noam, Lindholm, Dan
Julkaistu 2012

Induction of autophagy-dependent necroptosis is required for childhood acute lymphoblastic leukemia cells to overcome glucocorticoid resistance

Tekijä Bonapace, Laura, Bornhauser, Beat C., Schmitz, Maike, Cario, Gunnar, Ziegler, Urs, Niggli, Felix K., Schäfer, Beat W., Schrappe, Martin, Stanulla, Martin, Bourquin, Jean-Pierre
Julkaistu 2010

Image-based RNA interference screening reveals an individual dependence of acute lymphoblastic leukemia on stromal cysteine support

Tekijä Boutter, Jeannette, Huang, Yun, Marovca, Blerim, Vonderheit, Andreas, Grotzer, Michael A., Eckert, Cornelia, Cario, Gunnar, Wollscheid, Bernd, Horvath, Peter, Bornhauser, Beat C., Bourquin, Jean-Pierre
Julkaisussa Oncotarget (2014)

Clinical or ATPase domain mutations in ABCD4 disrupt the interaction between the vitamin B(12)-trafficking proteins ABCD4 and LMBD1

Tekijä Fettelschoss, Victoria, Burda, Patricie, Sagné, Corinne, Coelho, David, De Laet, Corinne, Lutz, Seraina, Suormala, Terttu, Fowler, Brian, Pietrancosta, Nicolas, Gasnier, Bruno, Bornhauser, Beat, Froese, D. Sean, Baumgartner, Matthias R.
Julkaisussa J Biol Chem (2017)

CD133 Positive Embryonal Rhabdomyosarcoma Stem-Like Cell Population Is Enriched in Rhabdospheres

Tekijä Walter, Dagmar, Satheesha, Sampoorna, Albrecht, Patrick, Bornhauser, Beat C., D'Alessandro, Valentina, Oesch, Susanne M., Rehrauer, Hubert, Leuschner, Ivo, Koscielniak, Ewa, Gengler, Carole, Moch, Holger, Bernasconi, Michele, Niggli, Felix K., Schäfer, Beat W.
Julkaistu 2011

Frequency and prognostic impact of ZEB2 H1038 and Q1072 mutations in childhood B-other acute lymphoblastic leukemia

Tekijä Zaliova, Marketa, Potuckova, Eliska, Lukes, Julius, Winkowska, Lucie, Starkova, Julia, Janotova, Iveta, Sramkova, Lucie, Stary, Jan, Zuna, Jan, Stanulla, Martin, Zimmermann, Martin, Bornhauser, Beat, Bourquin, Jean-Pierre, Eckert, Cornelia, Cario, Gunnar, Trka, Jan
Julkaisussa Haematologica (2020)

TNFR2 is required for RIP1-dependent cell death in human leukemia

Tekijä Aguadé-Gorgorió, Júlia, McComb, Scott, Eckert, Cornelia, Guinot, Anna, Marovca, Blerim, Mezzatesta, Caterina, Jenni, Silvia, Abduli, Liridon, Schrappe, Martin, Dobay, Maria Pamela, Stanulla, Martin, von Stackelberg, Arend, Cario, Gunnar, Bourquin, Jean-Pierre, Bornhauser, Beat C.
Julkaisussa Blood Adv (2020)

Cooperative Enhancer Activation by TLX1 and STAT5 Drives Development of NUP214-ABL1/TLX1-Positive T Cell Acute Lymphoblastic Leukemia

Tekijä Vanden Bempt, Marlies, Demeyer, Sofie, Broux, Michaël, De Bie, Jolien, Bornschein, Simon, Mentens, Nicole, Vandepoel, Roel, Geerdens, Ellen, Radaelli, Enrico, Bornhauser, Beat C., Kulozik, Andreas E., Meijerink, Jules P., Bourquin, Jean-Pierre, de Bock, Charles E., Cools, Jan
Julkaisussa Cancer Cell (2018)

Repurposing anthelmintic agents to eradicate resistant leukemia

Tekijä Mezzatesta, Caterina, Abduli, Liridon, Guinot, Anna, Eckert, Cornelia, Schewe, Denis, Zaliova, Marketa, Vinti, Luciana, Marovca, Blerim, Tsai, Yi-Chien, Jenni, Silvia, Aguade-Gorgorio, Julia, von Stackelberg, Arend, Schrappe, Martin, Locatelli, Franco, Stanulla, Martin, Cario, Gunnar, Bourquin, Jean-Pierre, Bornhauser, Beat C.
Julkaisussa Blood Cancer J (2020)

Pharmacological disruption of the Notch transcription factor complex

Tekijä Lehal, Rajwinder, Zaric, Jelena, Vigolo, Michele, Urech, Charlotte, Frismantas, Viktoras, Zangger, Nadine, Cao, Linlin, Berger, Adeline, Chicote, Irene, Loubéry, Sylvain, Choi, Sung Hee, Koch, Ute, Blacklow, Stephen C., Palmer, Hector G., Bornhauser, Beat, González-Gaitán, Marcos, Arsenijevic, Yvan, Zoete, Vincent, Aster, Jon C., Bourquin, Jean-Pierre, Radtke, Freddy
Julkaisussa Proc Natl Acad Sci U S A (2020)

Cell and Molecular Determinants of In Vivo Efficacy of the BH3 Mimetic ABT-263 Against Pediatric Acute Lymphoblastic Leukemia Xenografts

Tekijä Suryani, Santi, Carol, Hernan, Chonghaile, Triona Ni, Frismantas, Viktoras, Sarmah, Chintanu, High, Laura, Bornhauser, Beat, Cowley, Mark J, Szymanska, Barbara, Evans, Kathryn, Boehm, Ingrid, Tonna, Elise, Jones, Luke, Manesh, Donya Moradi, Kurmasheva, Raushan T., Billups, Catherine, Kaplan, Warren, Letai, Anthony, Bourquin, Jean-Pierre, Houghton, Peter J, Smith, Malcolm A, Lock, Richard B
Julkaistu 2014

RNA interference efficiently targets human leukemia driven by a fusion oncogene in vivo

Tekijä Jyotsana, Nidhi, Sharma, Amit, Chaturvedi, Anuhar, Scherr, Michaela, Kuchenbauer, Florian, Sajti, Laszlo, Barchanski, Annette, Lindner, Robert, Noyan, Fatih, Sühs, Kurt-Wolfram, Grote-Koska, Denis, Brand, Korbinian, Vornlocher, Hans-Peter, Stanulla, Martin, Bornhauser, Beat, Bourquin, Jean-Pierre, Eder, Matthias, Thol, Felicitas, Ganser, Arnold, Humphries, R. Keith, Ramsay, Euan, Cullis, Pieter, Heuser, Michael
Julkaisussa Leukemia (2017)

Prediction of venetoclax activity in precursor B-ALL by functional assessment of apoptosis signaling

Tekijä Seyfried, Felix, Demir, Salih, Hörl, Rebecca Louise, Stirnweiß, Felix Uli, Ryan, Jeremy, Scheffold, Annika, Villalobos-Ortiz, Mariana, Boldrin, Elena, Zinngrebe, Julia, Enzenmüller, Stefanie, Jenni, Silvia, Tsai, Yi-Chien, Bornhauser, Beat, Fürstberger, Axel, Kraus, Johann Michael, Kestler, Hans Armin, Bourquin, Jean-Pierre, Stilgenbauer, Stephan, Letai, Anthony, Debatin, Klaus-Michael, Meyer, Lüder Hinrich
Julkaisussa Cell Death Dis (2019)

DYRK1A regulates B cell acute lymphoblastic leukemia through phosphorylation of FOXO1 and STAT3

Tekijä Bhansali, Rahul S., Rammohan, Malini, Lee, Paul, Laurent, Anouchka P., Wen, Qiang, Suraneni, Praveen, Yip, Bon Ham, Tsai, Yi-Chien, Jenni, Silvia, Bornhauser, Beat, Siret, Aurélie, Fruit, Corinne, Pacheco-Benichou, Alexandra, Harris, Ethan, Besson, Thierry, Thompson, Benjamin J., Goo, Young Ah, Hijiya, Nobuko, Vilenchik, Maria, Izraeli, Shai, Bourquin, Jean-Pierre, Malinge, Sébastien, Crispino, John D.
Julkaisussa J Clin Invest (2021)