Exploiting Necroptosis for Therapy of Acute Lymphoblastic Leukemia

af Mezzatesta, Caterina, Bornhauser, Beat C.
Udgivet i Front Cell Dev Biol (2019)

Tissue Expression and Actin Binding of a Novel N-Terminal Utrophin Isoform

af Zuellig, Richard A., Bornhauser, Beat C., Amstutz, Ralf, Constantin, Bruno, Schaub, Marcus C.
Udgivet 2011

Rapid Generation of Leukemogenic Chromosomal Translocations in Vivo Using CRISPR/Cas9

af Huang, Yun, Marovca, Blerim, Dettwiler, Susanne, Bode, Peter Karl, Bornhauser, Beat, Bourquin, Jean-Pierre
Udgivet i Hemasphere (2020)

PDGF regulates the actin cytoskeleton through hnRNP-K-mediated activation of the ubiquitin E(3)-ligase MIR

af Nagano, Kohji, Bornhauser, Beat C, Warnasuriya, Gayathri, Entwistle, Alan, Cramer, Rainer, Lindholm, Dan, Naaby-Hansen, Soren
Udgivet 2006

Venetoclax and Bortezomib in Relapsed/Refractory Early T-Cell Precursor Acute Lymphoblastic Leukemia

af La Starza, Roberta, Cambò, Benedetta, Pierini, Antonio, Bornhauser, Beat, Montanaro, Anna, Bourquin, Jean-Pierre, Mecucci, Cristina, Roti, Giovanni
Udgivet i JCO Precis Oncol (2019)

Efficient apoptosis requires feedback amplification of upstream apoptotic signals by effector caspase-3 or -7

af McComb, Scott, Chan, Pik Ki, Guinot, Anna, Hartmannsdottir, Holmfridur, Jenni, Silvia, Dobay, Maria Pamela, Bourquin, Jean-Pierre, Bornhauser, Beat C.
Udgivet i Sci Adv (2019)

Fibroblast Growth Factor-21 (FGF21) Regulates Low-density Lipoprotein Receptor (LDLR) Levels in Cells via the E3-ubiquitin Ligase Mylip/Idol and the Canopy2 (Cnpy2)/Mylip-interacti...

af Do, Hai Thi, Tselykh, Timofey V., Mäkelä, Johanna, Ho, Tho Huu, Olkkonen, Vesa M., Bornhauser, Beat C., Korhonen, Laura, Zelcer, Noam, Lindholm, Dan
Udgivet 2012

Induction of autophagy-dependent necroptosis is required for childhood acute lymphoblastic leukemia cells to overcome glucocorticoid resistance

af Bonapace, Laura, Bornhauser, Beat C., Schmitz, Maike, Cario, Gunnar, Ziegler, Urs, Niggli, Felix K., Schäfer, Beat W., Schrappe, Martin, Stanulla, Martin, Bourquin, Jean-Pierre
Udgivet 2010

Image-based RNA interference screening reveals an individual dependence of acute lymphoblastic leukemia on stromal cysteine support

af Boutter, Jeannette, Huang, Yun, Marovca, Blerim, Vonderheit, Andreas, Grotzer, Michael A., Eckert, Cornelia, Cario, Gunnar, Wollscheid, Bernd, Horvath, Peter, Bornhauser, Beat C., Bourquin, Jean-Pierre
Udgivet i Oncotarget (2014)

Clinical or ATPase domain mutations in ABCD4 disrupt the interaction between the vitamin B(12)-trafficking proteins ABCD4 and LMBD1

af Fettelschoss, Victoria, Burda, Patricie, Sagné, Corinne, Coelho, David, De Laet, Corinne, Lutz, Seraina, Suormala, Terttu, Fowler, Brian, Pietrancosta, Nicolas, Gasnier, Bruno, Bornhauser, Beat, Froese, D. Sean, Baumgartner, Matthias R.
Udgivet i J Biol Chem (2017)

CD133 Positive Embryonal Rhabdomyosarcoma Stem-Like Cell Population Is Enriched in Rhabdospheres

af Walter, Dagmar, Satheesha, Sampoorna, Albrecht, Patrick, Bornhauser, Beat C., D'Alessandro, Valentina, Oesch, Susanne M., Rehrauer, Hubert, Leuschner, Ivo, Koscielniak, Ewa, Gengler, Carole, Moch, Holger, Bernasconi, Michele, Niggli, Felix K., Schäfer, Beat W.
Udgivet 2011

Frequency and prognostic impact of ZEB2 H1038 and Q1072 mutations in childhood B-other acute lymphoblastic leukemia

af Zaliova, Marketa, Potuckova, Eliska, Lukes, Julius, Winkowska, Lucie, Starkova, Julia, Janotova, Iveta, Sramkova, Lucie, Stary, Jan, Zuna, Jan, Stanulla, Martin, Zimmermann, Martin, Bornhauser, Beat, Bourquin, Jean-Pierre, Eckert, Cornelia, Cario, Gunnar, Trka, Jan
Udgivet i Haematologica (2020)

TNFR2 is required for RIP1-dependent cell death in human leukemia

af Aguadé-Gorgorió, Júlia, McComb, Scott, Eckert, Cornelia, Guinot, Anna, Marovca, Blerim, Mezzatesta, Caterina, Jenni, Silvia, Abduli, Liridon, Schrappe, Martin, Dobay, Maria Pamela, Stanulla, Martin, von Stackelberg, Arend, Cario, Gunnar, Bourquin, Jean-Pierre, Bornhauser, Beat C.
Udgivet i Blood Adv (2020)

Cooperative Enhancer Activation by TLX1 and STAT5 Drives Development of NUP214-ABL1/TLX1-Positive T Cell Acute Lymphoblastic Leukemia

af Vanden Bempt, Marlies, Demeyer, Sofie, Broux, Michaël, De Bie, Jolien, Bornschein, Simon, Mentens, Nicole, Vandepoel, Roel, Geerdens, Ellen, Radaelli, Enrico, Bornhauser, Beat C., Kulozik, Andreas E., Meijerink, Jules P., Bourquin, Jean-Pierre, de Bock, Charles E., Cools, Jan
Udgivet i Cancer Cell (2018)

Repurposing anthelmintic agents to eradicate resistant leukemia

af Mezzatesta, Caterina, Abduli, Liridon, Guinot, Anna, Eckert, Cornelia, Schewe, Denis, Zaliova, Marketa, Vinti, Luciana, Marovca, Blerim, Tsai, Yi-Chien, Jenni, Silvia, Aguade-Gorgorio, Julia, von Stackelberg, Arend, Schrappe, Martin, Locatelli, Franco, Stanulla, Martin, Cario, Gunnar, Bourquin, Jean-Pierre, Bornhauser, Beat C.
Udgivet i Blood Cancer J (2020)

Pharmacological disruption of the Notch transcription factor complex

af Lehal, Rajwinder, Zaric, Jelena, Vigolo, Michele, Urech, Charlotte, Frismantas, Viktoras, Zangger, Nadine, Cao, Linlin, Berger, Adeline, Chicote, Irene, Loubéry, Sylvain, Choi, Sung Hee, Koch, Ute, Blacklow, Stephen C., Palmer, Hector G., Bornhauser, Beat, González-Gaitán, Marcos, Arsenijevic, Yvan, Zoete, Vincent, Aster, Jon C., Bourquin, Jean-Pierre, Radtke, Freddy
Udgivet i Proc Natl Acad Sci U S A (2020)

Cell and Molecular Determinants of In Vivo Efficacy of the BH3 Mimetic ABT-263 Against Pediatric Acute Lymphoblastic Leukemia Xenografts

af Suryani, Santi, Carol, Hernan, Chonghaile, Triona Ni, Frismantas, Viktoras, Sarmah, Chintanu, High, Laura, Bornhauser, Beat, Cowley, Mark J, Szymanska, Barbara, Evans, Kathryn, Boehm, Ingrid, Tonna, Elise, Jones, Luke, Manesh, Donya Moradi, Kurmasheva, Raushan T., Billups, Catherine, Kaplan, Warren, Letai, Anthony, Bourquin, Jean-Pierre, Houghton, Peter J, Smith, Malcolm A, Lock, Richard B
Udgivet 2014

RNA interference efficiently targets human leukemia driven by a fusion oncogene in vivo

af Jyotsana, Nidhi, Sharma, Amit, Chaturvedi, Anuhar, Scherr, Michaela, Kuchenbauer, Florian, Sajti, Laszlo, Barchanski, Annette, Lindner, Robert, Noyan, Fatih, Sühs, Kurt-Wolfram, Grote-Koska, Denis, Brand, Korbinian, Vornlocher, Hans-Peter, Stanulla, Martin, Bornhauser, Beat, Bourquin, Jean-Pierre, Eder, Matthias, Thol, Felicitas, Ganser, Arnold, Humphries, R. Keith, Ramsay, Euan, Cullis, Pieter, Heuser, Michael
Udgivet i Leukemia (2017)

Prediction of venetoclax activity in precursor B-ALL by functional assessment of apoptosis signaling

af Seyfried, Felix, Demir, Salih, Hörl, Rebecca Louise, Stirnweiß, Felix Uli, Ryan, Jeremy, Scheffold, Annika, Villalobos-Ortiz, Mariana, Boldrin, Elena, Zinngrebe, Julia, Enzenmüller, Stefanie, Jenni, Silvia, Tsai, Yi-Chien, Bornhauser, Beat, Fürstberger, Axel, Kraus, Johann Michael, Kestler, Hans Armin, Bourquin, Jean-Pierre, Stilgenbauer, Stephan, Letai, Anthony, Debatin, Klaus-Michael, Meyer, Lüder Hinrich
Udgivet i Cell Death Dis (2019)

DYRK1A regulates B cell acute lymphoblastic leukemia through phosphorylation of FOXO1 and STAT3

af Bhansali, Rahul S., Rammohan, Malini, Lee, Paul, Laurent, Anouchka P., Wen, Qiang, Suraneni, Praveen, Yip, Bon Ham, Tsai, Yi-Chien, Jenni, Silvia, Bornhauser, Beat, Siret, Aurélie, Fruit, Corinne, Pacheco-Benichou, Alexandra, Harris, Ethan, Besson, Thierry, Thompson, Benjamin J., Goo, Young Ah, Hijiya, Nobuko, Vilenchik, Maria, Izraeli, Shai, Bourquin, Jean-Pierre, Malinge, Sébastien, Crispino, John D.
Udgivet i J Clin Invest (2021)