Cell-Based Small-Molecule Compound Screen Identifies Fenretinide as Potential Therapeutic for Translocation-Positive Rhabdomyosarcoma

Por Herrero Martín, David, Boro, Aleksandar, Schäfer, Beat W.
Publicado em 2013

ESF-EMBO Symposium “Molecular Biology and Innovative Therapies in Sarcomas of Childhood and Adolescence” Sept 29–Oct 4, Polonia Castle Pultusk, Poland

Por Schäfer, Beat W., Koscielniak, Ewa, Kovar, Heinrich, Fulda, Simone
Publicado em 2013

Induction of apoptosis in rhabdomyosarcoma cells through down-regulation of PAX proteins

Por Bernasconi, Michele, Remppis, Andrew, Fredericks, William J., Rauscher, Frank J., Schäfer, Beat W.
Publicado em 1996

The transcriptional activator PAX3-FKHR rescues the defects of Pax3 mutant mice but induces a myogenic gain-of-function phenotype with ligand-independent activation of Met signalin...

Por Relaix, Frédéric, Polimeni, Mariarosa, Rocancourt, Didier, Ponzetto, Carola, Schäfer, Beat W., Buckingham, Margaret
Publicado em 2003

Furin Targeted Drug Delivery for Treatment of Rhabdomyosarcoma in a Mouse Model

Por Hajdin, Katarina, D'Alessandro, Valentina, Niggli, Felix K., Schäfer, Beat W., Bernasconi, Michele
Publicado em 2010

Dral Is a P53-Responsive Gene Whose Four and a Half Lim Domain Protein Product Induces Apoptosis

Por Scholl, Florence A., McLoughlin, Patricia, Ehler, Elisabeth, de Giovanni, Carla, Schäfer, Beat W.
Publicado em 2000

The Proprotein Convertase Furin Contributes to Rhabdomyosarcoma Malignancy by Promoting Vascularization, Migration and Invasion

Por Jaaks, Patricia, D’Alessandro, Valentina, Grob, Nicole, Büel, Sina, Hajdin, Katarina, Schäfer, Beat W., Bernasconi, Michele
Publicado no PLoS One (2016)

Proteasomal Degradation of the EWS-FLI1 Fusion Protein Is Regulated by a Single Lysine Residue

Por Gierisch, Maria E., Pfistner, Franziska, Lopez-Garcia, Laura A., Harder, Lena, Schäfer, Beat W., Niggli, Felix K.
Publicado no J Biol Chem (2016)

PI3K/AKT signaling modulates transcriptional expression of EWS/FLI1 through specificity protein 1

Por Giorgi, Chiara, Boro, Aleksandar, Rechfeld, Florian, Lopez-Garcia, Laura A., Gierisch, Maria E., Schäfer, Beat W., Niggli, Felix K.
Publicado no Oncotarget (2015)

The proprotein convertase furin is required to maintain viability of alveolar rhabdomyosarcoma cells

Por Jaaks, Patricia, Meier, Gianmarco, Alijaj, Nagjie, Brack, Eva, Bode, Peter, Koscielniak, Ewa, Wachtel, Marco, Schäfer, Beat W., Bernasconi, Michele
Publicado no Oncotarget (2016)

Helicase CHD4 is an epigenetic coregulator of PAX3-FOXO1 in alveolar rhabdomyosarcoma

Por Böhm, Maria, Wachtel, Marco, Marques, Joana G., Streiff, Natalie, Laubscher, Dominik, Nanni, Paolo, Mamchaoui, Kamel, Santoro, Raffaella, Schäfer, Beat W.
Publicado no J Clin Invest (2016)

Induction of autophagy-dependent necroptosis is required for childhood acute lymphoblastic leukemia cells to overcome glucocorticoid resistance

Por Bonapace, Laura, Bornhauser, Beat C., Schmitz, Maike, Cario, Gunnar, Ziegler, Urs, Niggli, Felix K., Schäfer, Beat W., Schrappe, Martin, Stanulla, Martin, Bourquin, Jean-Pierre
Publicado em 2010

Targeting the EWS-ETS transcriptional program by BET bromodomain inhibition in Ewing sarcoma

Por Hensel, Tim, Giorgi, Chiara, Schmidt, Oxana, Calzada-Wack, Julia, Neff, Frauke, Buch, Thorsten, Niggli, Felix K., Schäfer, Beat W., Burdach, Stefan, Richter, Günther H.S.
Publicado no Oncotarget (2015)

CD133 Positive Embryonal Rhabdomyosarcoma Stem-Like Cell Population Is Enriched in Rhabdospheres

Por Walter, Dagmar, Satheesha, Sampoorna, Albrecht, Patrick, Bornhauser, Beat C., D'Alessandro, Valentina, Oesch, Susanne M., Rehrauer, Hubert, Leuschner, Ivo, Koscielniak, Ewa, Gengler, Carole, Moch, Holger, Bernasconi, Michele, Niggli, Felix K., Schäfer, Beat W.
Publicado em 2011

Rhabdomyosarcoma: Current Challenges and Their Implications for Developing Therapies

Por Hettmer, Simone, Li, Zhizhong, Billin, Andrew N., Barr, Frederic G., Cornelison, D.D.W., Ehrlich, Alan R., Guttridge, Denis C., Hayes-Jordan, Andrea, Helman, Lee J., Houghton, Peter J., Khan, Javed, Langenau, David M., Linardic, Corinne M., Pal, Ranadip, Partridge, Terence A., Pavlath, Grace K., Rota, Rossella, Schäfer, Beat W., Shipley, Janet, Stillman, Bruce, Wexler, Leonard H., Wagers, Amy J., Keller, Charles
Publicado em 2014

The First European Interdisciplinary Ewing Sarcoma Research Summit

Por Kovar, Heinrich, Alonso, Javier, Aman, Pierre, Aryee, Dave N. T., Ban, Jozef, Burchill, Sue A., Burdach, Stefan, De Alava, Enrique, Delattre, Olivier, Dirksen, Uta, Fourtouna, Argyro, Fulda, Simone, Helman, Lee J., Herrero-Martin, David, Hogendoorn, Pancras C. W., Kontny, Udo, Lawlor, Elizabeth R., Lessnick, Stephen L., Llombart-Bosch, Antonio, Metzler, Markus, Moriggl, Richard, Niedan, Stephan, Potratz, Jenny, Redini, Françoise, Richter, Günther H. S., Riedmann, Lucia T., Rossig, Claudia, Schäfer, Beat W., Schwentner, Raphaela, Scotlandi, Katia, Sorensen, Poul H., Staege, Martin S., Tirode, Franck, Toretsky, Jeffrey, Ventura, Selena, Eggert, Angelika, Ladenstein, Ruth
Publicado em 2012

The second European interdisciplinary Ewing sarcoma research summit – A joint effort to deconstructing the multiple layers of a complex disease

Por Kovar, Heinrich, Amatruda, James, Brunet, Erika, Burdach, Stefan, Cidre-Aranaz, Florencia, de Alava, Enrique, Dirksen, Uta, van der Ent, Wietske, Grohar, Patrick, Grünewald, Thomas G. P., Helman, Lee, Houghton, Peter, Iljin, Kristiina, Korsching, Eberhard, Ladanyi, Marc, Lawlor, Elizabeth, Lessnick, Stephen, Ludwig, Joseph, Meltzer, Paul, Metzler, Markus, Mora, Jaume, Moriggl, Richard, Nakamura, Takuro, Papamarkou, Theodore, Sarikas, Branka Radic, Rédini, Francoise, Richter, Guenther H. S., Rossig, Claudia, Schadler, Keri, Schäfer, Beat W., Scotlandi, Katia, Sheffield, Nathan C., Shelat, Anang, Snaar-Jagalska, Ewa, Sorensen, Poul, Stegmaier, Kimberly, Stewart, Elizabeth, Sweet-Cordero, Alejandro, Szuhai, Karoly, Tirado, Oscar M., Tirode, Franck, Toretsky, Jeffrey, Tsafou, Kalliopi, Üren, Aykut, Zinovyev, Andrei, Delattre, Olivier
Publicado no Oncotarget (2016)