Stratification and prediction of drug synergy based on target functional similarity

Por Yang, Mi, Jaaks, Patricia, Dry, Jonathan, Garnett, Mathew, Menden, Michael P., Saez-Rodriguez, Julio
Publicado no NPJ Syst Biol Appl (2020)

The Proprotein Convertase Furin Contributes to Rhabdomyosarcoma Malignancy by Promoting Vascularization, Migration and Invasion

Por Jaaks, Patricia, D’Alessandro, Valentina, Grob, Nicole, Büel, Sina, Hajdin, Katarina, Schäfer, Beat W., Bernasconi, Michele
Publicado no PLoS One (2016)

Patient‐specific logic models of signaling pathways from screenings on cancer biopsies to prioritize personalized combination therapies

Por Eduati, Federica, Jaaks, Patricia, Wappler, Jessica, Cramer, Thorsten, Merten, Christoph A, Garnett, Mathew J, Saez‐Rodriguez, Julio
Publicado no Mol Syst Biol (2020)

Patient‐specific logic models of signaling pathways from screenings on cancer biopsies to prioritize personalized combination therapies

Por Eduati, Federica, Jaaks, Patricia, Wappler, Jessica, Cramer, Thorsten, Merten, Christoph A, Garnett, Mathew J, Saez‐Rodriguez, Julio
Publicado no Mol Syst Biol (2020)

The proprotein convertase furin is required to maintain viability of alveolar rhabdomyosarcoma cells

Por Jaaks, Patricia, Meier, Gianmarco, Alijaj, Nagjie, Brack, Eva, Bode, Peter, Koscielniak, Ewa, Wachtel, Marco, Schäfer, Beat W., Bernasconi, Michele
Publicado no Oncotarget (2016)

USP19 deubiquitinates EWS-FLI1 to regulate Ewing sarcoma growth

Por Gierisch, Maria E., Pedot, Gloria, Walser, Franziska, Lopez-Garcia, Laura A., Jaaks, Patricia, Niggli, Felix K., Schäfer, Beat W.
Publicado no Sci Rep (2019)

Transcription factor activities enhance markers of drug sensitivity in cancer

Por Garcia-Alonso, Luz, Iorio, Francesco, Matchan, Angela, Fonseca, Nuno, Jaaks, Patricia, Peat, Gareth, Pignatelli, Miguel, Falcone, Fiammetta, Benes, Cyril H., Dunham, Ian, Bignell, Graham, McDade, Simon S., Garnett, Mathew J., Saez-Rodriguez, Julio
Publicado no Cancer Res (2018)

Integrated cross-study datasets of genetic dependencies in cancer

Por Pacini, Clare, Dempster, Joshua M., Boyle, Isabella, Gonçalves, Emanuel, Najgebauer, Hanna, Karakoc, Emre, van der Meer, Dieudonne, Barthorpe, Andrew, Lightfoot, Howard, Jaaks, Patricia, McFarland, James M., Garnett, Mathew J., Tsherniak, Aviad, Iorio, Francesco
Publicado no Nat Commun (2021)

SLFN11 informs on standard of care and novel treatments in a wide range of cancer models

Por Winkler, Claudia, Armenia, Joshua, Jones, Gemma N., Tobalina, Luis, Sale, Matthew J., Petreus, Tudor, Baird, Tarrion, Serra, Violeta, Wang, Anderson T., Lau, Alan, Garnett, Mathew J., Jaaks, Patricia, Coker, Elizabeth A., Pierce, Andrew J., O’Connor, Mark J., Leo, Elisabetta
Publicado no Br J Cancer (2020)

Drug mechanism‐of‐action discovery through the integration of pharmacological and CRISPR screens

Por Gonçalves, Emanuel, Segura‐Cabrera, Aldo, Pacini, Clare, Picco, Gabriele, Behan, Fiona M, Jaaks, Patricia, Coker, Elizabeth A, van der Meer, Donny, Barthorpe, Andrew, Lightfoot, Howard, Mironenko, Tatiana, Beck, Alexandra, Richardson, Laura, Yang, Wanjuan, Lleshi, Ermira, Hall, James, Tolley, Charlotte, Hall, Caitlin, Mali, Iman, Thomas, Frances, Morris, James, Leach, Andrew R, Lynch, James T, Sidders, Ben, Crafter, Claire, Iorio, Francesco, Fawell, Stephen, Garnett, Mathew J
Publicado no Mol Syst Biol (2020)