Exosomes in Bone Sarcomas: Key Players in Metastasis

by Chicón-Bosch, Mariona, Tirado, Oscar M.
Published in Cells (2020)

Auto-stimulatory action of secreted caveolin-1 on the proliferation of Ewing’s sarcoma cells

by Sengupta, Aniruddha, Mateo-Lozano, Silvia, Tirado, Oscar M., Notario, Vicente
Published 2011

The dual inhibitory effect of thiostrepton on FoxM1 and EWS/FLI1 provides a novel therapeutic option for Ewing’s sarcoma

by SENGUPTA, ANIRUDDHA, RAHMAN, MAHBUBUR, MATEO-LOZANO, SILVIA, TIRADO, OSCAR M., NOTARIO, VICENTE
Published 2013

PCPH/ENTPD5 expression confers to prostate cancer cells resistance against cisplatin-induced apoptosis through PKCα-mediated Bcl-2 stabilization

by Villar, Joaquín, Quadri, Humair S., Song, Insun, Tomita, York, Tirado, Oscar M., Notario, Vicente
Published 2009

Caveolin-1 promotes resistance to chemotherapy-induced apoptosis in Ewing’s sarcoma cells by modulating PKCα phosphorylation

by Tirado, Oscar M., MacCarthy, Caitlin M., Fatima, Naheed, Villar, Joaquín, Mateo-Lozano, Silvia, Notario, Vicente
Published 2010

Caveolin-1 in sarcomas: friend or foe?

by Sáinz-Jaspeado, Miguel, Martin-Liberal, Juan, Lagares-Tena, Laura, Mateo-Lozano, Silvia, del Muro, Xavier Garcia, Tirado, Oscar M
Published 2011

Targeted Therapies in Sarcomas: Challenging the Challenge

by Martín Liberal, Juan, Lagares-Tena, Laura, Sáinz-Jaspeado, Miguel, Mateo-Lozano, Silvia, García del Muro, Xavier, Tirado, Oscar M.
Published 2012

Bcl-x(L) inhibition enhances Dinaciclib-induced cell death in soft-tissue sarcomas

by Rello-Varona, Santi, Fuentes-Guirado, Miriam, López-Alemany, Roser, Contreras-Pérez, Aida, Mulet-Margalef, Núria, García-Monclús, Silvia, Tirado, Oscar M., García del Muro, Xavier
Published in Sci Rep (2019)

Pyrazolo[1,5-a]-1,3,5-triazine as a purine bioisostere: access to potent CDK inhibitor (R)-roscovitine analogue

by Popowycz, Florence, Fournet, Guy, Schneider, Cédric, Bettayeb, Karima, Ferandin, Yoan, Lamigeon, Cyrile, Tirado, Oscar M., Mateo-Lozano, Silvia, Notario, Vicente, Colas, Pierre, Bernard, Philippe, Meijer, Laurent, Joseph, Benoît
Published 2009

Caveolin-1 modulates the ability of Ewing's sarcoma to metastasize

by Sáinz-Jaspeado, Miguel, Lagares-Tena, Laura, Lasheras, Jaime, Navid, Fariba, Rodriguez-Galindo, Carlos, Mateo-Lozano, Silvia, Notario, Vicente, Sanjuan, Xavier, del Muro, Xavier Garcia, Fabra, Àngels, Tirado, Oscar M
Published 2010

EphA2-Induced Angiogenesis in Ewing Sarcoma Cells Works through bFGF Production and Is Dependent on Caveolin-1

by Sáinz-Jaspeado, Miguel, Huertas-Martinez, Juan, Lagares-Tena, Laura, Martin Liberal, Juan, Mateo-Lozano, Silvia, de Alava, Enrique, de Torres, Carmen, Mora, Jaume, del Muro, Xavier Garcia, Tirado, Oscar M.
Published 2013

Caveolin-1 promotes Ewing sarcoma metastasis regulating MMP-9 expression through MAPK/ERK pathway

by Lagares-Tena, Laura, García-Monclús, Silvia, López-Alemany, Roser, Almacellas-Rabaiget, Olga, Huertas-Martínez, Juan, Sáinz-Jaspeado, Miguel, Mateo-Lozano, Silvia, Rodríguez-Galindo, Carlos, Rello-Varona, Santiago, Herrero-Martín, David, Tirado, Oscar M.
Published in Oncotarget (2016)

The combination of epigenetic drugs SAHA and HCI-2509 synergistically inhibits EWS-FLI1 and tumor growth in Ewing sarcoma

by García-Domínguez, Daniel Jose, Hontecillas-Prieto, Lourdes, Rodríguez-Núñez, Pablo, Pascual-Pasto, Guillem, Vila-Ubach, Monica, García-Mejías, Rosa, Robles, María José, Tirado, Oscar M., Mora, Jaume, Carcaboso, Angel M., de Álava, Enrique
Published in Oncotarget (2018)

EphA2 receptor is a key player in the metastatic onset of Ewing sarcoma

by Garcia-Monclús, Silvia, López-Alemany, Roser, Almacellas-Rabaiget, Olga, Herrero-Martín, David, Huertas-Martinez, Juan, Lagares-Tena, Laura, Alba-Pavón, Piedad, Hontecillas-Prieto, Lourdes, Mora, Jaume, de Álava, Enrique, Rello-Varona, Santi, Giangrande, Paloma H., Tirado, Oscar M
Published in Int J Cancer (2018)

RING1B recruits EWSR1-FLI1 and cooperates in the remodeling of chromatin necessary for Ewing sarcoma tumorigenesis

by Sánchez-Molina, Sara, Figuerola-Bou, Elisabet, Blanco, Enrique, Sánchez-Jiménez, María, Táboas, Pablo, Gómez, Soledad, Ballaré, Cecilia, García-Domínguez, Daniel J., Prada, Estela, Hontecillas-Prieto, Lourdes, M. Carcaboso, Ángel, Tirado, Óscar M., Hernández-Muñoz, Inmaculada, de Álava, Enrique, Lavarino, Cinzia, Di Croce, Luciano, Mora, Jaume
Published in Sci Adv (2020)

RING1B contributes to Ewing sarcoma development by repressing the Na(V)1.6 sodium channel and the NF-κB pathway, independently of the fusion oncoprotein

by Hernandez-Muñoz, Inmaculada, Figuerola, Elisabeth, Sanchez-Molina, Sara, Rodriguez, Eva, Fernández-Mariño, Ana Isabel, Pardo-Pastor, Carlos, Bahamonde, María Isabel, Fernández-Fernández, José M., García-Domínguez, Daniel J., Hontecillas-Prieto, Lourdes, Lavarino, Cinzia, Carcaboso, Angel M., de Torres, Carmen, Tirado, Oscar M., de Alava, Enrique, Mora, Jaume
Published in Oncotarget (2016)

Caveolin-1 is down-regulated in alveolar rhabdomyosarcomas and negatively regulates tumor growth

by Huertas-Martínez, Juan, Rello-Varona, Santiago, Herrero-Martín, David, Barrau, Ignasi, García-Monclús, Silvia, Sáinz-Jaspeado, Miguel, Lagares-Tena, Laura, Núñez-Álvarez, Yaiza, Mateo-Lozano, Silvia, Mora, Jaume, Roma, Josep, Toran, Nuria, Moran, Sebastian, López-Alemany, Roser, Gallego, Soledad, Esteller, Manel, Peinado, Miguel A., Xavier García del, Muro, Tirado, Oscar M.
Published in Oncotarget (2014)

The transcribed pseudogene RPSAP52 enhances the oncofetal HMGA2-IGF2BP2-RAS axis through LIN28B-dependent and independent let-7 inhibition

by Oliveira-Mateos, Cristina, Sánchez-Castillo, Anaís, Soler, Marta, Obiols-Guardia, Aida, Piñeyro, David, Boque-Sastre, Raquel, Calleja-Cervantes, Maria E., Castro de Moura, Manuel, Martínez-Cardús, Anna, Rubio, Teresa, Pelletier, Joffrey, Martínez-Iniesta, Maria, Herrero-Martín, David, Tirado, Oscar M., Gentilella, Antonio, Villanueva, Alberto, Esteller, Manel, Farré, Lourdes, Guil, Sonia
Published in Nat Commun (2019)

The PARP inhibitor olaparib enhances the sensitivity of Ewing sarcoma to trabectedin

by Ordóñez, José Luis, Amaral, Ana Teresa, Carcaboso, Angel M., Herrero-Martín, David, García-Macías, María del Carmen, Sevillano, Vicky, Alonso, Diego, Pascual-Pasto, Guillem, San-Segundo, Laura, Vila-Ubach, Monica, Rodrigues, Telmo, Fraile, Susana, Teodosio, Cristina, Mayo-Iscar, Agustín, Aracil, Miguel, Galmarini, Carlos María, Tirado, Oscar M., Mora, Jaume, de Álava, Enrique
Published in Oncotarget (2015)

Correction: The PARP inhibitor olaparib enhances the sensitivity of Ewing sarcoma to trabectedin

by Ordóñez, José Luis, Amaral, Ana Teresa, Carcaboso, Angel M., Herrero-Martín, David, García-Macías, María del Carmen, Sevillano, Vicky, Alonso, Diego, Pascual-Pasto, Guillem, San-Segundo, Laura, Vila-Ubach, Monica, Rodrigues, Telmo, Fraile, Susana, Teodosio, Cristina, Mayo-Iscar, Agustín, Aracil, Miguel, Galmarini, Carlos María, Tirado, Oscar M., Mora, Jaume, de Álava, Enrique
Published in Oncotarget (2017)