Aberrant DNA methylation profiles in the premature aging disorders Hutchinson-Gilford Progeria and Werner syndrome

Por Heyn, Holger, Moran, Sebastian, Esteller, Manel
Publicado em 2013

Validation of a DNA methylation microarray for 850,000 CpG sites of the human genome enriched in enhancer sequences

Por Moran, Sebastian, Arribas, Carles, Esteller, Manel
Publicado no Epigenomics (2016)

Epigenetic mechanisms involved in melanoma pathogenesis and chemoresistance

Por Martinez-Cardús, Anna, Vizoso, Miguel, Moran, Sebastian, Manzano, Jose Luis
Publicado no Ann Transl Med (2015)

Validation of DNA methylation profiling in formalin-fixed paraffin-embedded samples using the Infinium HumanMethylation450 Microarray

Por Moran, Sebastián, Vizoso, Miguel, Martinez-Cardús, Anna, Gomez, Antonio, Matías-Guiu, Xavier, Chiavenna, Sebastián M, Fernandez, Andrés G, Esteller, Manel
Publicado em 2014

Genome-wide DNA methylation profiling predicts relapse in childhood B-cell acute lymphoblastic leukaemia

Por Sandoval, Juan, Heyn, Holger, Méndez-González, Jesús, Gomez, Antonio, Moran, Sebastian, Baiget, Montserrat, Melo, Montserrat, Badell, Isabel, Nomdedéu, Josep F, Esteller, Manel
Publicado em 2013

DNA methylation contributes to natural human variation

Por Heyn, Holger, Moran, Sebastian, Hernando-Herraez, Irene, Sayols, Sergi, Gomez, Antonio, Sandoval, Juan, Monk, Dave, Hata, Kenichiro, Marques-Bonet, Tomas, Wang, Liewei, Esteller, Manel
Publicado em 2013

Epigenetic inactivation of the putative DNA/RNA helicase SLFN11 in human cancer confers resistance to platinum drugs

Por Nogales, Vanesa, Reinhold, William C., Varma, Sudhir, Martinez-Cardus, Anna, Moutinho, Catia, Moran, Sebastian, Heyn, Holger, Sebio, Ana, Barnadas, Agusti, Pommier, Yves, Esteller, Manel
Publicado no Oncotarget (2015)

DNA methylation profiling in breast cancer discordant identical twins identifies DOK7 as novel epigenetic biomarker

Por Heyn, Holger, Carmona, F. Javier, Gomez, Antonio, Ferreira, Humberto J., Bell, Jordana T., Sayols, Sergi, Ward, Kirsten, Stefansson, Olafur A., Moran, Sebastian, Sandoval, Juan, Eyfjord, Jorunn E., Spector, Tim D., Esteller, Manel
Publicado em 2013

Whole-genome bisulfite DNA sequencing of a DNMT3B mutant patient

Por Heyn, Holger, Vidal, Enrique, Sayols, Sergi, Sanchez-Mut, Jose V., Moran, Sebastian, Medina, Ignacio, Sandoval, Juan, Simó-Riudalbas, Laia, Szczesna, Karolina, Huertas, Dori, Gatto, Sole, Matarazzo, Maria R., Dopazo, Joaquin, Esteller, Manel
Publicado em 2012

Variable maternal methylation overlapping the nc886/vtRNA2-1 locus is locked between hypermethylated repeats and is frequently altered in cancer

Por Romanelli, Valeria, Nakabayashi, Kazuhiko, Vizoso, Miguel, Moran, Sebastián, Iglesias-Platas, Isabel, Sugahara, Naoko, Sugahara, Naoko, Simón, Carlos, Simón, Carlos, Hata, Kenichiro, Hata, Kenichiro, Esteller, Manel, Esteller, Manel, Court, Franck, Court, Franck, Monk, David, Monk, David
Publicado em 2014

Arachidonic and oleic acid exert distinct effects on the DNA methylome

Por Silva-Martínez, Guillermo A., Rodríguez-Ríos, Dalia, Alvarado-Caudillo, Yolanda, Vaquero, Alejandro, Esteller, Manel, Carmona, F. Javier, Moran, Sebastian, Nielsen, Finn C., Wickström-Lindholm, Marie, Wrobel, Katarzyna, Wrobel, Kazimierz, Barbosa-Sabanero, Gloria, Zaina, Silvio, Lund, Gertrud
Publicado no Epigenetics (2016)

The NCI-60 Methylome and its Integration into CellMiner

Por Reinhold, William C., Varma, Sudhir, Sunshine, Margot, Rajapakse, Vinodh, Luna, Augustin, Kohn, Kurt W., Stevenson, Holly, Wang, Yonghong, Heyn, Holger, Nogales, Vanesa, Moran, Sebastian, Goldstein, David J., Doroshow, James H., Meltzer, Paul S., Esteller, Manel, Pommier, Yves
Publicado no Cancer Res (2016)

Identification of a new locus and validation of previously reported loci showing differential methylation associated with smoking. The REGICOR study

Por Sayols-Baixeras, Sergi, Lluís-Ganella, Carla, Subirana, Isaac, Salas, Lucas A, Vilahur, Nadia, Corella, Dolores, Muñoz, Dani, Segura, Antonio, Jimenez-Conde, Jordi, Moran, Sebastián, Soriano-Tárraga, Carolina, Roquer, Jaume, Lopez-Farré, Antonio, Marrugat, Jaume, Fitó, Montse, Elosua, Roberto
Publicado no Epigenetics (2015)

Aberrant DNA methylation in non-small cell lung cancer-associated fibroblasts

Por Vizoso, Miguel, Puig, Marta, Carmona, F.Javier, Maqueda, María, Velásquez, Adriana, Gómez, Antonio, Labernadie, Anna, Lugo, Roberto, Gabasa, Marta, Rigat-Brugarolas, Luis G., Trepat, Xavier, Ramírez, Josep, Moran, Sebastian, Vidal, Enrique, Reguart, Noemí, Perera, Alexandre, Esteller, Manel, Alcaraz, Jordi
Publicado no Carcinogenesis (2015)

The DNA methylation drift of the atherosclerotic aorta increases with lesion progression

Por Valencia-Morales, María del Pilar, Zaina, Silvio, Heyn, Holger, Carmona, F Javier, Varol, Nuray, Sayols, Sergi, Condom, Enric, Ramírez-Ruz, José, Gomez, Antonio, Moran, Sebastian, Lund, Gertrud, Rodríguez-Ríos, Dalia, López-González, Gladys, Ramírez-Nava, Magda, de la Rocha, Carmen, Sanchez-Flores, Alejandro, Esteller, Manel
Publicado no BMC Med Genomics (2015)

Epigenomic analysis detects aberrant super-enhancer DNA methylation in human cancer

Por Heyn, Holger, Vidal, Enrique, Ferreira, Humberto J., Vizoso, Miguel, Sayols, Sergi, Gomez, Antonio, Moran, Sebastian, Boque-Sastre, Raquel, Guil, Sonia, Martinez-Cardus, Anna, Lin, Charles Y., Royo, Romina, Sanchez-Mut, Jose V., Martinez, Ramon, Gut, Marta, Torrents, David, Orozco, Modesto, Gut, Ivo, Young, Richard A., Esteller, Manel
Publicado no Genome Biol (2016)

Caveolin-1 is down-regulated in alveolar rhabdomyosarcomas and negatively regulates tumor growth

Por Huertas-Martínez, Juan, Rello-Varona, Santiago, Herrero-Martín, David, Barrau, Ignasi, García-Monclús, Silvia, Sáinz-Jaspeado, Miguel, Lagares-Tena, Laura, Núñez-Álvarez, Yaiza, Mateo-Lozano, Silvia, Mora, Jaume, Roma, Josep, Toran, Nuria, Moran, Sebastian, López-Alemany, Roser, Gallego, Soledad, Esteller, Manel, Peinado, Miguel A., Xavier García del, Muro, Tirado, Oscar M.
Publicado no Oncotarget (2014)

Distinct DNA methylomes of newborns and centenarians

Por Heyn, Holger, Li, Ning, Ferreira, Humberto J., Moran, Sebastian, Pisano, David G., Gomez, Antonio, Diez, Javier, Sanchez-Mut, Jose V., Setien, Fernando, Carmona, F. Javier, Puca, Annibale A., Sayols, Sergi, Pujana, Miguel A., Serra-Musach, Jordi, Iglesias-Platas, Isabel, Formiga, Francesc, Fernandez, Agustin F., Fraga, Mario F., Heath, Simon C., Valencia, Alfonso, Gut, Ivo G., Wang, Jun, Esteller, Manel
Publicado em 2012

H3K4me1 marks DNA regions hypomethylated during aging in human stem and differentiated cells

Por Fernández, Agustín F., Bayón, Gustavo F., Urdinguio, Rocío G., Toraño, Estela G., García, María G., Carella, Antonella, Petrus-Reurer, Sandra, Ferrero, Cecilia, Martinez-Camblor, Pablo, Cubillo, Isabel, García-Castro, Javier, Delgado-Calle, Jesús, Pérez-Campo, Flor M., Riancho, José A., Bueno, Clara, Menéndez, Pablo, Mentink, Anouk, Mareschi, Katia, Claire, Fabian, Fagnani, Corrado, Medda, Emanuela, Toccaceli, Virgilia, Brescianini, Sonia, Moran, Sebastián, Esteller, Manel, Stolzing, Alexandra, de Boer, Jan, Nisticò, Lorenza, Stazi, Maria A., Fraga, Mario F.
Publicado no Genome Res (2015)

Epigenetic activation of a cryptic TBC1D16 transcript enhances melanoma progression by targeting EGFR

Por Vizoso, Miguel, Ferreira, Humberto J, Lopez-Serra, Paula, Javier Carmona, F, Martínez-Cardús, Anna, Girotti, Maria Romina, Villanueva, Alberto, Guil, Sonia, Moutinho, Catia, Liz, Julia, Portela, Anna, Heyn, Holger, Moran, Sebastian, Vidal, August, Martinez-Iniesta, Maria, Manzano, Jose L, Fernandez-Figueras, Maria Teresa, Elez, Elena, Muñoz-Couselo, Eva, Botella-Estrada, Rafael, Berrocal, Alfonso, Pontén, Fredrik, van den Oord, Joost, Gallagher, William M, Frederick, Dennie T, Flaherty, Keith T, McDermott, Ultan, Lorigan, Paul, Marais, Richard, Esteller, Manel
Publicado no Nat Med (2015)