Profiling of oxBS-450K 5-hydroxymethylcytosine in human placenta and brain reveals enrichment at imprinted loci

DNA methylation (5-methylcytosine, 5 mC) is involved in many cellular processes and is an epigenetic mechanism primarily associated with transcriptional repression. The recent discovery that 5 mC can be oxidized to 5-hydromethylcytosine (5hmC) by TET proteins has revealed the “sixth base” of DNA and...

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Bibliographic Details
Published in:Epigenetics
Main Authors: Hernandez Mora, Jose Ramon, Sanchez-Delgado, Marta, Petazzi, Paolo, Moran, Sebastian, Esteller, Manel, Iglesias-Platas, Isabel, Monk, David
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2018
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5873360/
https://ncbi.nlm.nih.gov/pubmed/28678681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2017.1344803
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