oxBS-MLE: an efficient method to estimate 5-methylcytosine and 5-hydroxymethylcytosine in paired bisulfite and oxidative bisulfite treated DNA

Motivation: 5-Methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) are important epigenetic regulators of gene expression. 5mC and 5hmC levels can be computationally inferred at single base resolution using sequencing or array data from paired DNA samples that have undergone bisulfite and oxidati...

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Gepubliceerd in:Bioinformatics
Hoofdauteurs: Xu, Zongli, Taylor, Jack A., Leung, Yuet-Kin, Ho, Shuk-Mei, Niu, Liang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2016
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Applications Notes
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5181539/
https://ncbi.nlm.nih.gov/pubmed/27522082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw527
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