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oxBS-MLE: an efficient method to estimate 5-methylcytosine and 5-hydroxymethylcytosine in paired bisulfite and oxidative bisulfite treated DNA

Motivation: 5-Methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) are important epigenetic regulators of gene expression. 5mC and 5hmC levels can be computationally inferred at single base resolution using sequencing or array data from paired DNA samples that have undergone bisulfite and oxidati...

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Detalles Bibliográficos
Publicado en:Bioinformatics
Main Authors: Xu, Zongli, Taylor, Jack A., Leung, Yuet-Kin, Ho, Shuk-Mei, Niu, Liang
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5181539/
https://ncbi.nlm.nih.gov/pubmed/27522082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw527
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