Oxidative bisulfite sequencing of 5-methylcytosine and 5-hydroxymethylcytosine

To uncover the function of and interplay between the mammalian cytosine modifications 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC), new techniques and advances in current technology are needed. To this end, we have developed oxidative bisulfite sequencing (oxBs-seq), which can quantitat...

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Autori principali: Booth, Michael J, Ost, Tobias W B, Beraldi, Dario, Bell, Neil M, Branco, Miguel R, Reik, Wolf, Balasubramanian, Shankar
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3919000/
https://ncbi.nlm.nih.gov/pubmed/24008380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2013.115
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