OxyBS: estimation of 5-methylcytosine and 5-hydroxymethylcytosine from tandem-treated oxidative bisulfite and bisulfite DNA

Summary: The use of sodium bisulfite (BS) treatment followed by hybridization to an Illumina Infinium BeadChip (HumanMethylation450 and MethylationEPIC) is a common method for interrogating 5-methylcytosine (5mC) at single nucleotide resolution. However, standard treatment of DNA with BS does not al...

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Publicado en:Bioinformatics
Autores principales: Houseman, E. Andres, Johnson, Kevin C., Christensen, Brock C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4978924/
https://ncbi.nlm.nih.gov/pubmed/27153596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw158
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