A symbiotic liaison between the genetic and epigenetic code

Por Heyn, Holger
Publicado em 2014

Quantitative Trait Loci Identify Functional Noncoding Variation in Cancer

Por Heyn, Holger
Publicado no PLoS Genet (2016)

Aberrant DNA methylation profiles in the premature aging disorders Hutchinson-Gilford Progeria and Werner syndrome

Por Heyn, Holger, Moran, Sebastian, Esteller, Manel
Publicado em 2013

CpG island hypermethylation-associated silencing of small nucleolar RNAs in human cancer

Por Ferreira, Humberto J., Heyn, Holger, Moutinho, Cátia, Esteller, Manel
Publicado em 2012

Novel Insights into DNA Methylation Features in Spermatozoa: Stability and Peculiarities

Por Krausz, Csilla, Sandoval, Juan, Sayols, Sergi, Chianese, Chiara, Giachini, Claudia, Heyn, Holger, Esteller, Manel
Publicado em 2012

Promoter Hypermethylation of the Phosphatase DUSP22 Mediates PKA-Dependent TAU Phosphorylation and CREB Activation in Alzheimer's Disease

Por Sanchez-Mut, Jose Vicente, Aso, Ester, Heyn, Holger, Matsuda, Tadashi, Bock, Christoph, Ferrer, Isidre, Esteller, Manel
Publicado no Hippocampus (2014)

Epigenetic Disruption of the PIWI Pathway in Human Spermatogenic Disorders

Por Heyn, Holger, Ferreira, Humberto J., Bassas, Lluís, Bonache, Sandra, Sayols, Sergi, Sandoval, Juan, Esteller, Manel, Larriba, Sara
Publicado em 2012

Epigenetic loss of the PIWI/piRNA machinery in human testicular tumorigenesis

Por Ferreira, Humberto J, Heyn, Holger, Garcia del Muro, Xavier, Vidal, August, Larriba, Sara, Muñoz, Clara, Villanueva, Alberto, Esteller, Manel
Publicado em 2014

Genome-wide DNA methylation profiling predicts relapse in childhood B-cell acute lymphoblastic leukaemia

Por Sandoval, Juan, Heyn, Holger, Méndez-González, Jesús, Gomez, Antonio, Moran, Sebastian, Baiget, Montserrat, Melo, Montserrat, Badell, Isabel, Nomdedéu, Josep F, Esteller, Manel
Publicado em 2013

DNA methylation contributes to natural human variation

Por Heyn, Holger, Moran, Sebastian, Hernando-Herraez, Irene, Sayols, Sergi, Gomez, Antonio, Sandoval, Juan, Monk, Dave, Hata, Kenichiro, Marques-Bonet, Tomas, Wang, Liewei, Esteller, Manel
Publicado em 2013

The interplay between DNA methylation and sequence divergence in recent human evolution

Por Hernando-Herraez, Irene, Heyn, Holger, Fernandez-Callejo, Marcos, Vidal, Enrique, Fernandez-Bellon, Hugo, Prado-Martinez, Javier, Sharp, Andrew J., Esteller, Manel, Marques-Bonet, Tomas
Publicado no Nucleic Acids Res (2015)

Epigenetic inactivation of the putative DNA/RNA helicase SLFN11 in human cancer confers resistance to platinum drugs

Por Nogales, Vanesa, Reinhold, William C., Varma, Sudhir, Martinez-Cardus, Anna, Moutinho, Catia, Moran, Sebastian, Heyn, Holger, Sebio, Ana, Barnadas, Agusti, Pommier, Yves, Esteller, Manel
Publicado no Oncotarget (2015)

Dynamics of DNA Methylation in Recent Human and Great Ape Evolution

Por Hernando-Herraez, Irene, Prado-Martinez, Javier, Garg, Paras, Fernandez-Callejo, Marcos, Heyn, Holger, Hvilsom, Christina, Navarro, Arcadi, Esteller, Manel, Sharp, Andrew J., Marques-Bonet, Tomas
Publicado em 2013

DNA methylation profiling in breast cancer discordant identical twins identifies DOK7 as novel epigenetic biomarker

Por Heyn, Holger, Carmona, F. Javier, Gomez, Antonio, Ferreira, Humberto J., Bell, Jordana T., Sayols, Sergi, Ward, Kirsten, Stefansson, Olafur A., Moran, Sebastian, Sandoval, Juan, Eyfjord, Jorunn E., Spector, Tim D., Esteller, Manel
Publicado em 2013

Whole-genome bisulfite DNA sequencing of a DNMT3B mutant patient

Por Heyn, Holger, Vidal, Enrique, Sayols, Sergi, Sanchez-Mut, Jose V., Moran, Sebastian, Medina, Ignacio, Sandoval, Juan, Simó-Riudalbas, Laia, Szczesna, Karolina, Huertas, Dori, Gatto, Sole, Matarazzo, Maria R., Dopazo, Joaquin, Esteller, Manel
Publicado em 2012

The NCI-60 Methylome and its Integration into CellMiner

Por Reinhold, William C., Varma, Sudhir, Sunshine, Margot, Rajapakse, Vinodh, Luna, Augustin, Kohn, Kurt W., Stevenson, Holly, Wang, Yonghong, Heyn, Holger, Nogales, Vanesa, Moran, Sebastian, Goldstein, David J., Doroshow, James H., Meltzer, Paul S., Esteller, Manel, Pommier, Yves
Publicado no Cancer Res (2016)

Single-cell transcriptome conservation in cryopreserved cells and tissues

Por Guillaumet-Adkins, Amy, Rodríguez-Esteban, Gustavo, Mereu, Elisabetta, Mendez-Lago, Maria, Jaitin, Diego A., Villanueva, Alberto, Vidal, August, Martinez-Marti, Alex, Felip, Enriqueta, Vivancos, Ana, Keren-Shaul, Hadas, Heath, Simon, Gut, Marta, Amit, Ido, Gut, Ivo, Heyn, Holger
Publicado no Genome Biol (2017)

The DNA methylation drift of the atherosclerotic aorta increases with lesion progression

Por Valencia-Morales, María del Pilar, Zaina, Silvio, Heyn, Holger, Carmona, F Javier, Varol, Nuray, Sayols, Sergi, Condom, Enric, Ramírez-Ruz, José, Gomez, Antonio, Moran, Sebastian, Lund, Gertrud, Rodríguez-Ríos, Dalia, López-González, Gladys, Ramírez-Nava, Magda, de la Rocha, Carmen, Sanchez-Flores, Alejandro, Esteller, Manel
Publicado no BMC Med Genomics (2015)

Epigenomic analysis detects aberrant super-enhancer DNA methylation in human cancer

Por Heyn, Holger, Vidal, Enrique, Ferreira, Humberto J., Vizoso, Miguel, Sayols, Sergi, Gomez, Antonio, Moran, Sebastian, Boque-Sastre, Raquel, Guil, Sonia, Martinez-Cardus, Anna, Lin, Charles Y., Royo, Romina, Sanchez-Mut, Jose V., Martinez, Ramon, Gut, Marta, Torrents, David, Orozco, Modesto, Gut, Ivo, Young, Richard A., Esteller, Manel
Publicado no Genome Biol (2016)

Epigenetic inactivation of the p53-induced long noncoding RNA TP53 target 1 in human cancer

Por Diaz-Lagares, Angel, Crujeiras, Ana B., Lopez-Serra, Paula, Soler, Marta, Setien, Fernando, Goyal, Ashish, Sandoval, Juan, Hashimoto, Yutaka, Martinez-Cardús, Anna, Gomez, Antonio, Heyn, Holger, Moutinho, Catia, Espada, Jesús, Vidal, August, Paúles, Maria, Galán, Maica, Sala, Núria, Akiyama, Yoshimitsu, Martínez-Iniesta, María, Farré, Lourdes, Villanueva, Alberto, Gross, Matthias, Diederichs, Sven, Guil, Sonia, Esteller, Manel
Publicado no Proc Natl Acad Sci U S A (2016)