The interplay between DNA methylation and sequence divergence in recent human evolution

Despite the increasing knowledge about DNA methylation, the understanding of human epigenome evolution is in its infancy. Using whole genome bisulfite sequencing we identified hundreds of differentially methylated regions (DMRs) in humans compared to non-human primates and estimated that ∼25% of the...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Hernando-Herraez, Irene, Heyn, Holger, Fernandez-Callejo, Marcos, Vidal, Enrique, Fernandez-Bellon, Hugo, Prado-Martinez, Javier, Sharp, Andrew J., Esteller, Manel, Marques-Bonet, Tomas
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Gene regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4787803/
https://ncbi.nlm.nih.gov/pubmed/26170231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv693
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