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CpG island hypermethylation-associated silencing of small nucleolar RNAs in human cancer

Much effort in cancer research has focused on the tiny part of our genome that codes for mRNA. However, it has recently been recognized that microRNAs also contribute decisively to tumorigenesis. Studies have also shown that epigenetic silencing by CpG island hypermethylation of microRNAs with tumor...

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Main Authors: Ferreira, Humberto J., Heyn, Holger, Moutinho, Cátia, Esteller, Manel
格式: Artigo
語言:Inglês
出版: Landes Bioscience 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3495749/
https://ncbi.nlm.nih.gov/pubmed/22617881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.19353
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