CpG island hypermethylation-associated silencing of non-coding RNAs transcribed from ultraconserved regions in human cancer

Although only 1.5% of the human genome appears to code for proteins, much effort in cancer research has been devoted to this minimal fraction of our DNA. However, the last few years have witnessed the realization that a large class of non-coding RNAs (ncRNAs), named microRNAs, contribute to cancer d...

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Detalhes bibliográficos
Main Authors: Lujambio, A, Portela, A, Liz, J, Melo, S A, Rossi, S, Spizzo, R, Croce, C M, Calin, G A, Esteller, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3007676/
https://ncbi.nlm.nih.gov/pubmed/20802525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.361
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