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CpG island hypermethylation-associated silencing of non-coding RNAs transcribed from ultraconserved regions in human cancer

Although only 1.5% of the human genome appears to code for proteins, much effort in cancer research has been devoted to this minimal fraction of our DNA. However, the last few years have witnessed the realization that a large class of non-coding RNAs (ncRNAs), named microRNAs, contribute to cancer d...

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Hlavní autoři: Lujambio, A, Portela, A, Liz, J, Melo, S A, Rossi, S, Spizzo, R, Croce, C M, Calin, G A, Esteller, M
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3007676/
https://ncbi.nlm.nih.gov/pubmed/20802525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.361
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