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CpG island hypermethylation in human astrocytomas

Astrocytomas are common and lethal human brain tumors. We have analyzed the methylation status of over 28,000 CpG islands and 18,000 promoters in normal human brain and in astrocytomas of various grades using the methylated-CpG island recovery assay (MIRA). We identified six to seven thousand methyl...

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Detalhes bibliográficos
Main Authors: Wu, Xiwei, Rauch, Tibor A., Zhong, Xueyan, Bennett, William P., Latif, Farida, Krex, Dietmar, Pfeifer, Gerd P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848870/
https://ncbi.nlm.nih.gov/pubmed/20233874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-3631
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