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CpG island hypermethylation in human astrocytomas

Astrocytomas are common and lethal human brain tumors. We have analyzed the methylation status of over 28,000 CpG islands and 18,000 promoters in normal human brain and in astrocytomas of various grades using the methylated-CpG island recovery assay (MIRA). We identified six to seven thousand methyl...

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Main Authors: Wu, Xiwei, Rauch, Tibor A., Zhong, Xueyan, Bennett, William P., Latif, Farida, Krex, Dietmar, Pfeifer, Gerd P.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848870/
https://ncbi.nlm.nih.gov/pubmed/20233874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-3631
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