Epigenetic loss of the PIWI/piRNA machinery in human testicular tumorigenesis

Although most cancer research has focused in mRNA, non-coding RNAs are also an essential player in tumorigenesis. In addition to the well-recognized microRNAs, recent studies have also shown that epigenetic silencing by CpG island hypermethylation of other classes of non-coding RNAs, such as transcr...

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Bibliographische Detailangaben
Hauptverfasser: Ferreira, Humberto J, Heyn, Holger, Garcia del Muro, Xavier, Vidal, August, Larriba, Sara, Muñoz, Clara, Villanueva, Alberto, Esteller, Manel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2014
Schlagworte:
Brief Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3928173/
https://ncbi.nlm.nih.gov/pubmed/24247010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.27237
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