Epigenomic analysis detects aberrant super-enhancer DNA methylation in human cancer

BACKGROUND: One of the hallmarks of cancer is the disruption of gene expression patterns. Many molecular lesions contribute to this phenotype, and the importance of aberrant DNA methylation profiles is increasingly recognized. Much of the research effort in this area has examined proximal promoter r...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Genome Biol
Main Authors: Heyn, Holger, Vidal, Enrique, Ferreira, Humberto J., Vizoso, Miguel, Sayols, Sergi, Gomez, Antonio, Moran, Sebastian, Boque-Sastre, Raquel, Guil, Sonia, Martinez-Cardus, Anna, Lin, Charles Y., Royo, Romina, Sanchez-Mut, Jose V., Martinez, Ramon, Gut, Marta, Torrents, David, Orozco, Modesto, Gut, Ivo, Young, Richard A., Esteller, Manel
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728783/
https://ncbi.nlm.nih.gov/pubmed/26813288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-0879-2
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker