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Epigenomic analysis detects aberrant super-enhancer DNA methylation in human cancer
BACKGROUND: One of the hallmarks of cancer is the disruption of gene expression patterns. Many molecular lesions contribute to this phenotype, and the importance of aberrant DNA methylation profiles is increasingly recognized. Much of the research effort in this area has examined proximal promoter r...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Genome Biol |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
BioMed Central
2016
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4728783/ https://ncbi.nlm.nih.gov/pubmed/26813288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-0879-2 |
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