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Aberrant DNA methylation profiles in the premature aging disorders Hutchinson-Gilford Progeria and Werner syndrome

DNA methylation gradiently changes with age and is likely to be involved in aging-related processes with subsequent phenotype changes and increased susceptibility to certain diseases. The Hutchinson-Gilford Progeria (HGP) and Werner Syndrome (WS) are two premature aging diseases showing features of...

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Detalhes bibliográficos
Main Authors: Heyn, Holger, Moran, Sebastian, Esteller, Manel
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549877/
https://ncbi.nlm.nih.gov/pubmed/23257959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.23366
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