Epigenetic mechanisms involved in melanoma pathogenesis and chemoresistance

Por Martinez-Cardús, Anna, Vizoso, Miguel, Moran, Sebastian, Manzano, Jose Luis
Publicado no Ann Transl Med (2015)

Validation of DNA methylation profiling in formalin-fixed paraffin-embedded samples using the Infinium HumanMethylation450 Microarray

Por Moran, Sebastián, Vizoso, Miguel, Martinez-Cardús, Anna, Gomez, Antonio, Matías-Guiu, Xavier, Chiavenna, Sebastián M, Fernandez, Andrés G, Esteller, Manel
Publicado em 2014

Resistant mechanisms to BRAF inhibitors in melanoma

Por Manzano, José Luís, Layos, Laura, Bugés, Cristina, de los Llanos Gil, María, Vila, Laia, Martínez-Balibrea, Eva, Martínez-Cardús, Anna
Publicado no Ann Transl Med (2016)

Epigenetic inactivation of the putative DNA/RNA helicase SLFN11 in human cancer confers resistance to platinum drugs

Por Nogales, Vanesa, Reinhold, William C., Varma, Sudhir, Martinez-Cardus, Anna, Moutinho, Catia, Moran, Sebastian, Heyn, Holger, Sebio, Ana, Barnadas, Agusti, Pommier, Yves, Esteller, Manel
Publicado no Oncotarget (2015)

PKM2 Subcellular Localization Is Involved in Oxaliplatin Resistance Acquisition in HT29 Human Colorectal Cancer Cell Lines

Por Ginés, Alba, Bystrup, Sara, Ruiz de Porras, Vicenç, Guardia, Cristina, Musulén, Eva, Martínez-Cardús, Anna, Manzano, José Luis, Layos, Laura, Abad, Albert, Martínez-Balibrea, Eva
Publicado no PLoS One (2015)

Curcumin mediates oxaliplatin-acquired resistance reversion in colorectal cancer cell lines through modulation of CXC-Chemokine/NF-κB signalling pathway

Por Ruiz de Porras, Vicenç, Bystrup, Sara, Martínez-Cardús, Anna, Pluvinet, Raquel, Sumoy, Lauro, Howells, Lynne, James, Mark I., Iwuji, Chinenye, Manzano, José Luis, Layos, Laura, Bugés, Cristina, Abad, Albert, Martínez-Balibrea, Eva
Publicado no Sci Rep (2016)

Epigenetic Inactivation of the BRCA1 Interactor SRBC and Resistance to Oxaliplatin in Colorectal Cancer

Por Moutinho, Catia, Martinez-Cardús, Anna, Santos, Cristina, Navarro-Pérez, Valentin, Martínez-Balibrea, Eva, Musulen, Eva, Carmona, F. Javier, Sartore-Bianchi, Andrea, Cassingena, Andrea, Siena, Salvatore, Elez, Elena, Tabernero, Josep, Salazar, Ramon, Abad, Albert, Esteller, Manel
Publicado em 2013

Epigenomic analysis detects aberrant super-enhancer DNA methylation in human cancer

Por Heyn, Holger, Vidal, Enrique, Ferreira, Humberto J., Vizoso, Miguel, Sayols, Sergi, Gomez, Antonio, Moran, Sebastian, Boque-Sastre, Raquel, Guil, Sonia, Martinez-Cardus, Anna, Lin, Charles Y., Royo, Romina, Sanchez-Mut, Jose V., Martinez, Ramon, Gut, Marta, Torrents, David, Orozco, Modesto, Gut, Ivo, Young, Richard A., Esteller, Manel
Publicado no Genome Biol (2016)

Epigenetic inactivation of the p53-induced long noncoding RNA TP53 target 1 in human cancer

Por Diaz-Lagares, Angel, Crujeiras, Ana B., Lopez-Serra, Paula, Soler, Marta, Setien, Fernando, Goyal, Ashish, Sandoval, Juan, Hashimoto, Yutaka, Martinez-Cardús, Anna, Gomez, Antonio, Heyn, Holger, Moutinho, Catia, Espada, Jesús, Vidal, August, Paúles, Maria, Galán, Maica, Sala, Núria, Akiyama, Yoshimitsu, Martínez-Iniesta, María, Farré, Lourdes, Villanueva, Alberto, Gross, Matthias, Diederichs, Sven, Guil, Sonia, Esteller, Manel
Publicado no Proc Natl Acad Sci U S A (2016)

A DERL3-associated defect in the degradation of SLC2A1 mediates the Warburg effect

Por Lopez-Serra, Paula, Marcilla, Miguel, Villanueva, Alberto, Ramos-Fernandez, Antonio, Palau, Anna, Leal, Lucía, Wahi, Jessica E., Setien-Baranda, Fernando, Szczesna, Karolina, Moutinho, Catia, Martinez-Cardus, Anna, Heyn, Holger, Sandoval, Juan, Puertas, Sara, Vidal, August, Sanjuan, Xavier, Martinez-Balibrea, Eva, Viñals, Francesc, Perales, Jose C., Bramsem, Jesper B., Ørntoft, Torben F., Andersen, Claus L., Tabernero, Josep, McDermott, Ultan, Boxer, Matthew B., Heiden, Matthew G. Vander, Albar, Juan Pablo, Esteller, Manel
Publicado em 2014

Corrigendum: A DERL3-associated defect in the degradation of SLC2A1 mediates the Warburg effect

Por Lopez-Serra, Paula, Marcilla, Miguel, Villanueva, Alberto, Ramos-Fernandez, Antonio, Palau, Anna, Leal, Lucía, Wahi, Jessica E., Setien-Baranda, Fernando, Szczesna, Karolina, Moutinho, Catia, Martinez-Cardus, Anna, Heyn, Holger, Sandoval, Juan, Puertas, Sara, Vidal, August, Sanjuan, Xavier, Martinez-Balibrea, Eva, Viñals, Francesc, Perales, Jose C., Bramsem, Jesper B., Ørntoft, Torben F., Andersen, Claus L., Tabernero, Josep, McDermott, Ultan, Boxer, Matthew B., Vander Heiden, Matthew G., Albar, Juan Pablo, Esteller, Manel
Publicado no Nat Commun (2016)

Epigenetic activation of a cryptic TBC1D16 transcript enhances melanoma progression by targeting EGFR

Por Vizoso, Miguel, Ferreira, Humberto J, Lopez-Serra, Paula, Javier Carmona, F, Martínez-Cardús, Anna, Girotti, Maria Romina, Villanueva, Alberto, Guil, Sonia, Moutinho, Catia, Liz, Julia, Portela, Anna, Heyn, Holger, Moran, Sebastian, Vidal, August, Martinez-Iniesta, Maria, Manzano, Jose L, Fernandez-Figueras, Maria Teresa, Elez, Elena, Muñoz-Couselo, Eva, Botella-Estrada, Rafael, Berrocal, Alfonso, Pontén, Fredrik, van den Oord, Joost, Gallagher, William M, Frederick, Dennie T, Flaherty, Keith T, McDermott, Ultan, Lorigan, Paul, Marais, Richard, Esteller, Manel
Publicado no Nat Med (2015)