PKM2 Subcellular Localization Is Involved in Oxaliplatin Resistance Acquisition in HT29 Human Colorectal Cancer Cell Lines

Chemoresistance is the main cause of treatment failure in advanced colorectal cancer (CRC). However, molecular mechanisms underlying this phenomenon remain to be elucidated. In a previous work we identified low levels of PKM2 as a putative oxaliplatin-resistance marker in HT29 CRC cell lines and als...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Ginés, Alba, Bystrup, Sara, Ruiz de Porras, Vicenç, Guardia, Cristina, Musulén, Eva, Martínez-Cardús, Anna, Manzano, José Luis, Layos, Laura, Abad, Albert, Martínez-Balibrea, Eva
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2015
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4425499/
https://ncbi.nlm.nih.gov/pubmed/25955657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123830
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