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Insulin caused drug resistance to oxaliplatin in colon cancer cell line HT29
INTRODUCTION: Obesity is associated with poor prognosis of colon cancer and the mechanism for this is unknown. This study tested insulin-caused resistance to oxaliplatin via activation of PI3K/Akt pathway in HT29 cells. METHODS: The effect of insulin on oxaliplatin cytotoxicity was tested by pre-inc...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Pioneer Bioscience Publishing Company
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3397588/ https://ncbi.nlm.nih.gov/pubmed/22811824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2078-6891.2010.028 |
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