Interactive effect of age and APOE-ε4 allele load on white matter myelin content in cognitively normal middle-aged subjects

The apolipoprotein E gene (APOE) ε4 allele has a strong and manifold impact on cognition and neuroimaging phenotypes in cognitively normal subjects, including alterations in the white matter (WM) microstructure. Such alterations have often been regarded as a reflection of potential thinning of the m...

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Detalhes bibliográficos
Publicado no:Neuroimage Clin
Main Authors: Operto, Grégory, Molinuevo, José Luis, Cacciaglia, Raffaele, Falcon, Carles, Brugulat-Serrat, Anna, Suárez-Calvet, Marc, Grau-Rivera, Oriol, Bargalló, Nuria, Morán, Sebastián, Esteller, Manel, Gispert, Juan Domingo
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6742967/
https://ncbi.nlm.nih.gov/pubmed/31520917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nicl.2019.101983
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