Factors Affecting EWS-FLI1 Activity in Ewing's Sarcoma

Por Herrero-Martin, David, Fourtouna, Argyro, Niedan, Stephan, Riedmann, Lucia T., Schwentner, Raphaela, Aryee, Dave N. T.
Publicado em 2011

EWS-FLI1 employs an E2F switch to drive target gene expression

Por Schwentner, Raphaela, Papamarkou, Theodore, Kauer, Maximilian O., Stathopoulos, Vassilios, Yang, Fan, Bilke, Sven, Meltzer, Paul S., Girolami, Mark, Kovar, Heinrich
Publicado no Nucleic Acids Res (2015)

Vemurafenib in Langerhans cell histiocytosis: report of a pediatric patient and review of the literature

Por Heisig, Anne, Sörensen, Jan, Zimmermann, Stefanie-Yvonne, Schöning, Stefan, Schwabe, Dirk, Kvasnicka, Hans-Michael, Schwentner, Raphaela, Hutter, Caroline, Lehrnbecher, Thomas
Publicado no Oncotarget (2018)

The role of miR-17-92 in the miRegulatory landscape of Ewing sarcoma

Por Schwentner, Raphaela, Herrero-Martin, David, Kauer, Maximilian O, Mutz, Cornelia N, Katschnig, Anna M, Sienski, Grzegorz, Alonso, Javier, Aryee, Dave NT, Kovar, Heinrich
Publicado no Oncotarget (2016)

Oncogenic ETS fusions deregulate E2F3 target genes in Ewing sarcoma and prostate cancer

Por Bilke, Sven, Schwentner, Raphaela, Yang, Fan, Kauer, Maximilian, Jug, Gunhild, Walker, Robert L., Davis, Sean, Zhu, Yuelin J., Pineda, Marbin, Meltzer, Paul S., Kovar, Heinrich
Publicado em 2013

Overexpression of HOX genes is prevalent in Ewing sarcoma and is associated with altered epigenetic regulation of developmental transcription programs

Por Svoboda, Laurie K, Harris, Ashley, Bailey, Natashay J, Schwentner, Raphaela, Tomazou, Eleni, von Levetzow, Cornelia, Magnuson, Brian, Ljungman, Mats, Kovar, Heinrich, Lawlor, Elizabeth R
Publicado no Epigenetics (2015)

EWS-FLI1 Suppresses NOTCH-Activated p53 in Ewing’s Sarcoma

Por Ban, Jozef, Bennani-Baiti, Idriss M., Kauer, Max, Schaefer, Karl-Ludwig, Poremba, Christopher, Jug, Gunhild, Schwentner, Raphaela, Smrzka, Oskar, Muehlbacher, Karin, Aryee, Dave N.T., Kovar, Heinrich
Publicado no Cancer Res (2008)

EWS‐FLI1 impairs aryl hydrocarbon receptor activation by blocking tryptophan breakdown via the kynurenine pathway

Por Mutz, Cornelia N., Schwentner, Raphaela, Kauer, Maximilian O., Katschnig, Anna M., Kromp, Florian, Aryee, Dave N. T., Erhardt, Sophie, Goiny, Michel, Alonso, Javier, Fuchs, Dietmar, Kovar, Heinrich
Publicado no FEBS Lett (2016)

Targeted inhibition of the MAPK pathway: emerging salvage option for progressive life-threatening multisystem LCH

Por Kolenová, Alexandra, Schwentner, Raphaela, Jug, Gunhild, Simonitsch-Klupp, Ingrid, Kornauth, Christoph, Plank, Lukáš, Horáková, Júlia, Bodová, Ivana, Sýkora, Tomáš, Geczová, Lucia, Holter, Wolfgang, Minkov, Milen, Hutter, Caroline
Publicado no Blood Adv (2017)

Hypoxia modulates EWS-FLI1 transcriptional signature and enhances malignant properties of Ewing's sarcoma cells in-vitro

Por Aryee, Dave N.T., Niedan, Stephan, Kauer, Maximilian, Schwentner, Raphaela, Bennani-Baiti, Idriss M., Ban, Jozef, Muehlbacher, Karin, Kreppel, Michael, Walker, Robert L., Meltzer, Paul, Poremba, Christopher, Kofler, Reinhard, Kovar, Heinrich
Publicado em 2010

Hsa-mir-145 is the top EWS-FLI1 repressed microRNA involved in a positive feed-back loop in Ewing’s sarcoma

Por Ban, Jozef, Jug, Gunhild, Mestdagh, Pieter, Schwentner, Raphaela, Kauer, Max, Aryee, Dave N.T., Schaefer, Karl-Ludwig, Nakatani, Fumihiko, Scotlandi, Katia, Reiter, Marlies, Strunk, Dirk, Speleman, Frank, Vandesompele, Jo, Kovar, Heinrich
Publicado no Oncogene (2011)

EWS-FLI1 confers exquisite sensitivity to NAMPT inhibition in Ewing sarcoma cells

Por Mutz, Cornelia N., Schwentner, Raphaela, Aryee, Dave N.T., Bouchard, Eric D.J., Mejia, Edgard M., Hatch, Grant M., Kauer, Maximilian O., Katschnig, Anna M., Ban, Jozef, Garten, Antje, Alonso, Javier, Banerji, Versha, Kovar, Heinrich
Publicado no Oncotarget (2017)

Epigenomics and Single-cell Sequencing Define a Developmental Hierarchy in Langerhans Cell Histiocytosis

Por Halbritter, Florian, Farlik, Matthias, Schwentner, Raphaela, Jug, Gunhild, Fortelny, Nikolaus, Schnöller, Thomas, Pisa, Hanja, Schuster, Linda C., Reinprecht, Andrea, Czech, Thomas, Gojo, Johannes, Holter, Wolfgang, Minkov, Milen, Bauer, Wolfgang, Simonitsch-Klupp, Ingrid, Bock, Christoph, Hutter, Caroline
Publicado no Cancer Discov (2019)

YAP/TAZ inhibition reduces metastatic potential of Ewing sarcoma cells

Por Bierbaumer, Lisa, Katschnig, Anna M., Radic-Sarikas, Branka, Kauer, Maximilian O., Petro, Jeffrey A., Högler, Sandra, Gurnhofer, Elisabeth, Pedot, Gloria, Schäfer, Beat W., Schwentner, Raphaela, Mühlbacher, Karin, Kromp, Florian, Aryee, Dave N. T., Kenner, Lukas, Uren, Aykut, Kovar, Heinrich
Publicado no Oncogenesis (2021)

Identifying the druggable interactome of EWS-FLI1 reveals MCL-1 dependent differential sensitivities of Ewing sarcoma cells to apoptosis inducers

Por Tsafou, Kalliopi, Katschnig, Anna Maria, Radic-Sarikas, Branka, Mutz, Cornelia Noëlle, Iljin, Kristiina, Schwentner, Raphaela, Kauer, Maximilian O., Mühlbacher, Karin, Aryee, Dave N.T., Westergaard, David, Haapa-Paananen, Saija, Fey, Vidal, Superti-Furga, Giulio, Toretsky, Jeffrey, Brunak, Søren, Kovar, Heinrich
Publicado no Oncotarget (2018)

Synthetic lethality between the cohesin subunits STAG1 and STAG2 in diverse cancer contexts

Por van der Lelij, Petra, Lieb, Simone, Jude, Julian, Wutz, Gordana, Santos, Catarina P, Falkenberg, Katrina, Schlattl, Andreas, Ban, Jozef, Schwentner, Raphaela, Hoffmann, Thomas, Kovar, Heinrich, Real, Francisco X, Waldman, Todd, Pearson, Mark A, Kraut, Norbert, Peters, Jan-Michael, Zuber, Johannes, Petronczki, Mark
Publicado no eLife (2017)

The First European Interdisciplinary Ewing Sarcoma Research Summit

Por Kovar, Heinrich, Alonso, Javier, Aman, Pierre, Aryee, Dave N. T., Ban, Jozef, Burchill, Sue A., Burdach, Stefan, De Alava, Enrique, Delattre, Olivier, Dirksen, Uta, Fourtouna, Argyro, Fulda, Simone, Helman, Lee J., Herrero-Martin, David, Hogendoorn, Pancras C. W., Kontny, Udo, Lawlor, Elizabeth R., Lessnick, Stephen L., Llombart-Bosch, Antonio, Metzler, Markus, Moriggl, Richard, Niedan, Stephan, Potratz, Jenny, Redini, Françoise, Richter, Günther H. S., Riedmann, Lucia T., Rossig, Claudia, Schäfer, Beat W., Schwentner, Raphaela, Scotlandi, Katia, Sorensen, Poul H., Staege, Martin S., Tirode, Franck, Toretsky, Jeffrey, Ventura, Selena, Eggert, Angelika, Ladenstein, Ruth
Publicado em 2012