EWS-FLI1 confers exquisite sensitivity to NAMPT inhibition in Ewing sarcoma cells

Ewing sarcoma (EwS) is the second most common bone cancer in children and adolescents with a high metastatic potential. EwS development is driven by a specific chromosomal translocation resulting in the generation of a chimeric EWS-ETS transcription factor, most frequently EWS-FLI1. Nicotinamide ade...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Mutz, Cornelia N., Schwentner, Raphaela, Aryee, Dave N.T., Bouchard, Eric D.J., Mejia, Edgard M., Hatch, Grant M., Kauer, Maximilian O., Katschnig, Anna M., Ban, Jozef, Garten, Antje, Alonso, Javier, Banerji, Versha, Kovar, Heinrich
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5421879/
https://ncbi.nlm.nih.gov/pubmed/28160567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14976
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