Nampt: Linking NAD biology, metabolism, and cancer

Por Garten, Antje, Petzold, Stefanie, Körner, Antje, Imai, Shin-ichiro, Kiess, Wieland
Publicado em 2008

Oleate ameliorates palmitate-induced reduction of NAMPT activity and NAD levels in primary human hepatocytes and hepatocarcinoma cells

Por Penke, Melanie, Schuster, Susanne, Gorski, Theresa, Gebhardt, Rolf, Kiess, Wieland, Garten, Antje
Publicado no Lipids Health Dis (2017)

Chemosensitization of leukemia cells through inhibition of NAMPT

Por Gorski, Theresa, Petzold-Quinque, Stefanie, Schuster, Susanne, Penke, Melanie, Richter, Sandy, Kiess, Wieland, Garten, Antje
Publicado em 2014

Resveratrol differentially regulates NAMPT and SIRT1 in hepatocarcinoma cells and primary human hepatocytes

Por Schuster, Susanne, Penke, Melanie, Gorski, Theresa, Barnikol-Oettler, Anja, Gebhardt, Rolf, Kiess, Wieland, Garten, Antje
Publicado em 2014

Short-term overfeeding of zebrafish with normal or high-fat diet as a model for the development of metabolically healthy versus unhealthy obesity

Por Landgraf, Kathrin, Schuster, Susanne, Meusel, Andrej, Garten, Antje, Riemer, Thomas, Schleinitz, Dorit, Kiess, Wieland, Körner, Antje
Publicado no BMC Physiol (2017)

Resveratrol Differentially Regulates NAMPT and SIRT1 in Hepatocarcinoma Cells and Primary Human Hepatocytes

Por Schuster, Susanne, Penke, Melanie, Gorski, Theresa, Petzold-Quinque, Stefanie, Damm, Georg, Gebhardt, Rolf, Kiess, Wieland, Garten, Antje
Publicado em 2014

Altered hepatic lipid metabolism in mice lacking both the melanocortin type 4 receptor and low density lipoprotein receptor

Por Lede, Vera, Meusel, Andrej, Garten, Antje, Popkova, Yulia, Penke, Melanie, Franke, Christin, Ricken, Albert, Schulz, Angela, Kiess, Wieland, Huster, Daniel, Schöneberg, Torsten, Schiller, Jürgen
Publicado no PLoS One (2017)

The Adipocytokine Nampt and Its Product NMN Have No Effect on Beta-Cell Survival but Potentiate Glucose Stimulated Insulin Secretion

Por Spinnler, Robert, Gorski, Theresa, Stolz, Katharina, Schuster, Susanne, Garten, Antje, Beck-Sickinger, Annette G., Engelse, Marten A., de Koning, Eelco J. P., Körner, Antje, Kiess, Wieland, Maedler, Kathrin
Publicado em 2013

Nampt/PBEF/visfatin regulates insulin secretion in β cells as a systemic NAD biosynthetic enzyme

Por Revollo, Javier R., Körner, Antje, Mills, Kathryn F., Satoh, Akiko, Wang, Tao, Garten, Antje, Dasgupta, Biplab, Sasaki, Yo, Wolberger, Cynthia, Townsend, R. Reid, Milbrandt, Jeffrey, Kiess, Wieland, Imai, Shin-ichiro
Publicado em 2007

Target enzyme mutations are the molecular basis for resistance towards pharmacological inhibition of nicotinamide phosphoribosyltransferase

Por Olesen, Uffe H, Petersen, Jakob G, Garten, Antje, Kiess, Wieland, Yoshino, Jun, Imai, Shin-Ichiro, Christensen, Mette K, Fristrup, Peter, Thougaard, Annemette V, Björkling, Fredrik, Jensen, Peter B, Nielsen, Søren J, Sehested, Maxwell
Publicado em 2010

EWS-FLI1 confers exquisite sensitivity to NAMPT inhibition in Ewing sarcoma cells

Por Mutz, Cornelia N., Schwentner, Raphaela, Aryee, Dave N.T., Bouchard, Eric D.J., Mejia, Edgard M., Hatch, Grant M., Kauer, Maximilian O., Katschnig, Anna M., Ban, Jozef, Garten, Antje, Alonso, Javier, Banerji, Versha, Kovar, Heinrich
Publicado no Oncotarget (2017)

Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells

Por Fletcher, Rachel S., Ratajczak, Joanna, Doig, Craig L., Oakey, Lucy A., Callingham, Rebecca, Da Silva Xavier, Gabriella, Garten, Antje, Elhassan, Yasir S., Redpath, Philip, Migaud, Marie E., Philp, Andrew, Brenner, Charles, Canto, Carles, Lavery, Gareth G.
Publicado no Mol Metab (2017)