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Resveratrol Differentially Regulates NAMPT and SIRT1 in Hepatocarcinoma Cells and Primary Human Hepatocytes

Resveratrol is reported to possess chemotherapeutic properties in several cancers. In this study, we wanted to investigate the molecular mechanisms of resveratrol-induced cell cycle arrest and apoptosis as well as the impact of resveratrol on NAMPT and SIRT1 protein function and asked whether there...

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Detalhes bibliográficos
Main Authors: Schuster, Susanne, Penke, Melanie, Gorski, Theresa, Petzold-Quinque, Stefanie, Damm, Georg, Gebhardt, Rolf, Kiess, Wieland, Garten, Antje
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946349/
https://ncbi.nlm.nih.gov/pubmed/24603648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0091045
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