Nampt/PBEF/visfatin regulates insulin secretion in β cells as a systemic NAD biosynthetic enzyme

SUMMARY: Intracellular nicotinamide phosphoribosyltransferase (iNampt) is an essential enzyme in the NAD biosynthetic pathway. An extracellular form of this protein (eNampt) has been reported to act as a cytokine named PBEF or an insulin-mimetic hormone named visfatin, but its physiological relevanc...

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Hlavní autoři: Revollo, Javier R., Körner, Antje, Mills, Kathryn F., Satoh, Akiko, Wang, Tao, Garten, Antje, Dasgupta, Biplab, Sasaki, Yo, Wolberger, Cynthia, Townsend, R. Reid, Milbrandt, Jeffrey, Kiess, Wieland, Imai, Shin-ichiro
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2098698/
https://ncbi.nlm.nih.gov/pubmed/17983582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2007.09.003
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