Hsa-mir-145 is the top EWS-FLI1 repressed microRNA involved in a positive feed-back loop in Ewing’s sarcoma

EWS-FLI1 is a chromosome translocation-derived chimeric transcription factor that plays a central and rate-limiting role in the pathogenesis of Ewing’s sarcoma. While the EWS-FLI1 transcriptomic signature has been extensively characterized on the mRNA level, information on its impact on non-coding R...

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Gepubliceerd in:Oncogene
Hoofdauteurs: Ban, Jozef, Jug, Gunhild, Mestdagh, Pieter, Schwentner, Raphaela, Kauer, Max, Aryee, Dave N.T., Schaefer, Karl-Ludwig, Nakatani, Fumihiko, Scotlandi, Katia, Reiter, Marlies, Strunk, Dirk, Speleman, Frank, Vandesompele, Jo, Kovar, Heinrich
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959567/
https://ncbi.nlm.nih.gov/pubmed/21217773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.581
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