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Oncogenic ETS fusions deregulate E2F3 target genes in Ewing sarcoma and prostate cancer
Deregulated E2F transcription factor activity occurs in the vast majority of human tumors and has been solidly implicated in disturbances of cell cycle control, proliferation, and apoptosis. Aberrant E2F regulatory activity is often caused by impairment of control through pRB function, but little is...
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Main Authors: | , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Cold Spring Harbor Laboratory Press
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3814880/ https://ncbi.nlm.nih.gov/pubmed/23940108 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.151340.112 |
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