Oncogenic ETS fusions deregulate E2F3 target genes in Ewing sarcoma and prostate cancer

Deregulated E2F transcription factor activity occurs in the vast majority of human tumors and has been solidly implicated in disturbances of cell cycle control, proliferation, and apoptosis. Aberrant E2F regulatory activity is often caused by impairment of control through pRB function, but little is...

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Main Authors: Bilke, Sven, Schwentner, Raphaela, Yang, Fan, Kauer, Maximilian, Jug, Gunhild, Walker, Robert L., Davis, Sean, Zhu, Yuelin J., Pineda, Marbin, Meltzer, Paul S., Kovar, Heinrich
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2013
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814880/
https://ncbi.nlm.nih.gov/pubmed/23940108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.151340.112
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