Oncogenic ETS fusions deregulate E2F3 target genes in Ewing sarcoma and prostate cancer

Deregulated E2F transcription factor activity occurs in the vast majority of human tumors and has been solidly implicated in disturbances of cell cycle control, proliferation, and apoptosis. Aberrant E2F regulatory activity is often caused by impairment of control through pRB function, but little is...

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Autors principals: Bilke, Sven, Schwentner, Raphaela, Yang, Fan, Kauer, Maximilian, Jug, Gunhild, Walker, Robert L., Davis, Sean, Zhu, Yuelin J., Pineda, Marbin, Meltzer, Paul S., Kovar, Heinrich
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2013
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814880/
https://ncbi.nlm.nih.gov/pubmed/23940108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.151340.112
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