Epigenomics and Single-cell Sequencing Define a Developmental Hierarchy in Langerhans Cell Histiocytosis

Langerhans cell histiocytosis (LCH) is a rare neoplasm predominantly affecting children. It occupies a hybrid position between cancers and inflammatory diseases, which makes it an attractive model for studying cancer development. To explore the molecular mechanisms underlying the pathophysiology of...

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Bibliographic Details
Published in:Cancer Discov
Main Authors: Halbritter, Florian, Farlik, Matthias, Schwentner, Raphaela, Jug, Gunhild, Fortelny, Nikolaus, Schnöller, Thomas, Pisa, Hanja, Schuster, Linda C., Reinprecht, Andrea, Czech, Thomas, Gojo, Johannes, Holter, Wolfgang, Minkov, Milen, Bauer, Wolfgang, Simonitsch-Klupp, Ingrid, Bock, Christoph, Hutter, Caroline
Format: Artigo
Language:Inglês
Published: 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6795548/
https://ncbi.nlm.nih.gov/pubmed/31345789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-19-0138
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