EWS-FLI1 employs an E2F switch to drive target gene expression

Cell cycle progression is orchestrated by E2F factors. We previously reported that in ETS-driven cancers of the bone and prostate, activating E2F3 cooperates with ETS on target promoters. The mechanism of target co-regulation remained unknown. Using RNAi and time-resolved chromatin-immunoprecipitati...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Schwentner, Raphaela, Papamarkou, Theodore, Kauer, Maximilian O., Stathopoulos, Vassilios, Yang, Fan, Bilke, Sven, Meltzer, Paul S., Girolami, Mark, Kovar, Heinrich
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Molecular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357724/
https://ncbi.nlm.nih.gov/pubmed/25712098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv123
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