Image-based RNA interference screening reveals an individual dependence of acute lymphoblastic leukemia on stromal cysteine support

Interactions with the bone marrow microenvironment are essential for leukemia survival and disease progression. We developed an imaging-based RNAi platform to identify protective cues from bone marrow derived mesenchymal stromal cells (MSC) that promote survival of primary acute lymphoblastic leukem...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Boutter, Jeannette, Huang, Yun, Marovca, Blerim, Vonderheit, Andreas, Grotzer, Michael A., Eckert, Cornelia, Cario, Gunnar, Wollscheid, Bernd, Horvath, Peter, Bornhauser, Beat C., Bourquin, Jean-Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294362/
https://ncbi.nlm.nih.gov/pubmed/25415224
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