Targeted editing of the PSIP1 gene encoding LEDGF/p75 protects cells against HIV infection

av Lampi, Yulia, Van Looveren, Dominique, Vranckx, Lenard S., Thiry, Irina, Bornschein, Simon, Debyser, Zeger, Gijsbers, Rik
I publikationen Sci Rep (2019)

Gain-of-function mutation in IFIH1 can cause both aicardi-goutières syndrome and systemic lupus erythematosus with IgA-deficiency

av Van Eyck, Lien, De Somer, Lien, Pombal, Diana, Bornschein, Simon, de Zegher, Francis, Liston, Adrian, Wouters, Carine
Publicerad 2014

Malt1 self‐cleavage is critical for regulatory T cell homeostasis and anti‐tumor immunity in mice

av Baens, Mathijs, Stirparo, Rocco, Lampi, Youlia, Verbeke, Delphine, Vandepoel, Roel, Cools, Jan, Marynen, Peter, de Bock, Charles E., Bornschein, Simon
I publikationen Eur J Immunol (2018)

The Long Non-coding RNA Flatr Anticipates Foxp3 Expression in Regulatory T Cells

av Brajic, Aleksandra, Franckaert, Dean, Burton, Oliver, Bornschein, Simon, Calvanese, Anna L., Demeyer, Sofie, Cools, Jan, Dooley, James, Schlenner, Susan, Liston, Adrian
I publikationen Front Immunol (2018)

Mutant JAK3 signaling is increased by loss of wild-type JAK3 or by acquisition of secondary JAK3 mutations in T-ALL

av Degryse, Sandrine, Bornschein, Simon, de Bock, Charles E., Leroy, Emilie, Vanden Bempt, Marlies, Demeyer, Sofie, Jacobs, Kris, Geerdens, Ellen, Gielen, Olga, Soulier, Jean, Harrison, Christine J., Constantinescu, Stefan N., Cools, Jan
I publikationen Blood (2018)

Cooperative Enhancer Activation by TLX1 and STAT5 Drives Development of NUP214-ABL1/TLX1-Positive T Cell Acute Lymphoblastic Leukemia

av Vanden Bempt, Marlies, Demeyer, Sofie, Broux, Michaël, De Bie, Jolien, Bornschein, Simon, Mentens, Nicole, Vandepoel, Roel, Geerdens, Ellen, Radaelli, Enrico, Bornhauser, Beat C., Kulozik, Andreas E., Meijerink, Jules P., Bourquin, Jean-Pierre, de Bock, Charles E., Cools, Jan
I publikationen Cancer Cell (2018)

A comprehensive inventory of TLX1 controlled long non-coding RNAs in T-cell acute lymphoblastic leukemia through polyA+ and total RNA sequencing

av Verboom, Karen, Van Loocke, Wouter, Volders, Pieter-Jan, Decaesteker, Bieke, Cobos, Francisco Avila, Bornschein, Simon, de Bock, Charles E., Atak, Zeynep Kalender, Clappier, Emmanuelle, Aerts, Stein, Cools, Jan, Soulier, Jean, Taghon, Tom, Van Vlierberghe, Pieter, Vandesompele, Jo, Speleman, Frank, Durinck, Kaat
I publikationen Haematologica (2018)

The T-cell leukemia associated ribosomal RPL10 R98S mutation enhances JAK-STAT signaling

av Girardi, Tiziana, Vereecke, Stijn, Sulima, Sergey O., Khan, Yousuf, Fancello, Laura, Briggs, Joseph W., Schwab, Claire, de Beeck, Joyce Op, Verbeeck, Jelle, Royaert, Jonathan, Geerdens, Ellen, Vicente, Carmen, Bornschein, Simon, Harrison, Christine J., Meijerink, Jules P., Cools, Jan, Dinman, Jonathan D., Kampen, Kim R., De Keersmaecker, Kim
I publikationen Leukemia (2017)