IntReALL HR and the benefits of adaptive design

Tekijä Holmes, Jane, Love, Sharon, Saha, Vaskar, von Stackelberg, Arend
Julkaisussa Trials (2015)

Copy number genome alterations are associated with treatment response and outcome in relapsed childhood ETV6/RUNX1-positive acute lymphoblastic leukemia

Tekijä Bokemeyer, Almut, Eckert, Cornelia, Meyr, Franziska, Koerner, Gabriele, von Stackelberg, Arend, Ullmann, Reinhard, Türkmen, Seval, Henze, Günter, Seeger, Karl
Julkaistu 2014

High VLA-4 expression is associated with adverse outcome and distinct gene expression changes in childhood B-cell precursor acute lymphoblastic leukemia at first relapse

Tekijä Shalapour, Shabnam, Hof, Jana, Kirschner-Schwabe, Renate, Bastian, Lorenz, Eckert, Cornelia, Prada, Javier, Henze, Günter, von Stackelberg, Arend, Seeger, Karl
Julkaistu 2011

Survival after blinatumomab treatment in pediatric patients with relapsed/refractory B-cell precursor acute lymphoblastic leukemia

Tekijä Gore, Lia, Locatelli, Franco, Zugmaier, Gerhard, Handgretinger, Rupert, O’Brien, Maureen M., Bader, Peter, Bhojwani, Deepa, Schlegel, Paul-Gerhardt, Tuglus, Catherine A., von Stackelberg, Arend
Julkaisussa Blood Cancer J (2018)

Primary central nervous system lymphoma in children and adolescents: low relapse rate after treatment according to Non-Hodgkin-Lymphoma Berlin-Frankfurt-Münster protocols for syste...

Tekijä Thorer, Heike, Zimmermann, Martin, Makarova, Olga, Oschlies, Ilske, Klapper, Wolfram, Lang, Peter, von Stackelberg, Arend, Fleischhack, Gudrun, Worch, Jennifer, Juergens, Heribert, Woessmann, Wilhelm, Reiter, Alfred, Burkhardt, Birgit
Julkaisussa Haematologica (2014)

Subclonal NT5C2 mutations are associated with poor outcomes after relapse of pediatric acute lymphoblastic leukemia

Tekijä Barz, Malwine J., Hof, Jana, Groeneveld-Krentz, Stefanie, Loh, Jui Wan, Szymansky, Annabell, Astrahantseff, Kathy, von Stackelberg, Arend, Khiabanian, Hossein, Ferrando, Adolfo A., Eckert, Cornelia, Kirschner-Schwabe, Renate
Julkaisussa Blood (2020)

Minimal residual disease analysis by eight-color flow cytometry in relapsed childhood acute lymphoblastic leukemia

Tekijä Karawajew, Leonid, Dworzak, Michael, Ratei, Richard, Rhein, Peter, Gaipa, Giuseppe, Buldini, Barbara, Basso, Giuseppe, Hrusak, Ondrej, Ludwig, Wolf-Dieter, Henze, Günter, Seeger, Karl, von Stackelberg, Arend, Mejstrikova, Ester, Eckert, Cornelia
Julkaisussa Haematologica (2015)

Pediatric Acute Lymphoblastic Leukemia: Efficacy and safety of recombinant E. coli-asparaginase in infants (less than one year of age) with acute lymphoblastic leukemia

Tekijä van der Sluis, Inge, Möricke, Anja, Escherich, Gabriele, von Stackelberg, Arend, Holter, Wolfgang, Klingebiel, Thomas, Flotho, Christian, Legien, Sabine, Tissing, Wim, Bierings, Marc, Guimbal-Schmolck, Cecile, Pichlmeier, Uwe, Kühnel, Hans-Jürgen, Pieters, Rob
Julkaistu 2013

Ras pathway mutations are prevalent in relapsed childhood acute lymphoblastic leukemia and confer sensitivity to MEK inhibition

Tekijä Irving, Julie, Matheson, Elizabeth, Minto, Lynne, Blair, Helen, Case, Marian, Halsey, Christina, Swidenbank, Isabella, Ponthan, Frida, Kirschner-Schwabe, Renate, Groeneveld-Krentz, Stefanie, Hof, Jana, Allan, James, Harrison, Christine, Vormoor, Josef, von Stackelberg, Arend, Eckert, Cornelia
Julkaisussa Blood (2014)

TNFR2 is required for RIP1-dependent cell death in human leukemia

Tekijä Aguadé-Gorgorió, Júlia, McComb, Scott, Eckert, Cornelia, Guinot, Anna, Marovca, Blerim, Mezzatesta, Caterina, Jenni, Silvia, Abduli, Liridon, Schrappe, Martin, Dobay, Maria Pamela, Stanulla, Martin, von Stackelberg, Arend, Cario, Gunnar, Bourquin, Jean-Pierre, Bornhauser, Beat C.
Julkaisussa Blood Adv (2020)

NOTCH1 mutation, TP53 alteration and myeloid antigen expression predict outcome heterogeneity in children with first relapse of T-cell acute lymphoblastic leukemia

Tekijä Hof, Jana, Kox, Corinne, Groeneveld-Krentz, Stefanie, Bandapalli, Obul R., Karawajew, Leonid, Schedel, Katharina, Kunz, Joachim B., Eckert, Cornelia, Ludwig, Wolf-Dieter, Ratei, Richard, Rhein, Peter, Henze, Günter, Muckenthaler, Martina U., Kulozik, Andreas E., von Stackelberg, Arend, Kirschner-Schwabe, Renate
Julkaisussa Haematologica (2017)

Repurposing anthelmintic agents to eradicate resistant leukemia

Tekijä Mezzatesta, Caterina, Abduli, Liridon, Guinot, Anna, Eckert, Cornelia, Schewe, Denis, Zaliova, Marketa, Vinti, Luciana, Marovca, Blerim, Tsai, Yi-Chien, Jenni, Silvia, Aguade-Gorgorio, Julia, von Stackelberg, Arend, Schrappe, Martin, Locatelli, Franco, Stanulla, Martin, Cario, Gunnar, Bourquin, Jean-Pierre, Bornhauser, Beat C.
Julkaisussa Blood Cancer J (2020)

Clinical and genetic characteristics of children with acute lymphoblastic leukemia and Li–Fraumeni syndrome

Tekijä Winter, Greta, Kirschner-Schwabe, Renate, Groeneveld-Krentz, Stefanie, Escherich, Gabriele, Möricke, Anja, von Stackelberg, Arend, Stanulla, Martin, Bailey, Simon, Richter, Lisa, Steinemann, Doris, Ripperger, Tim, Escudero, Adela, Farah, Roula, Lohi, Olli, Wadt, Karin, Jongmans, Marjolijn, van Engelen, Nienke, Eckert, Cornelia, Kratz, Christian Peter
Julkaisussa Leukemia (2021)

Durable remissions in TCF3-HLF positive acute lymphoblastic leukemia with blinatumomab and stem cell transplantation

Tekijä Mouttet, Brice, Vinti, Luciana, Ancliff, Philip, Bodmer, Nicole, Brethon, Benoît, Cario, Gunnar, Chen-Santel, Christiane, Elitzur, Sarah, Hazar, Volkan, Kunz, Joachim, Möricke, Anja, Stein, Jerry, Vora, Ajay, Yaman, Yöntem, Schrappe, Martin, Anak, Sema, Baruche, André, Locatelli, Franco, von Stackelberg, Arend, Stanulla, Martin, Bourquin, Jean-Pierre
Julkaisussa Haematologica (2019)

Blinatumomab versus historical standard therapy in pediatric patients with relapsed/refractory Ph-negative B-cell precursor acute lymphoblastic leukemia

Tekijä Locatelli, Franco, Whitlock, James A., Peters, Christina, Chen-Santel, Christiane, Chia, Victoria, Dennis, Robyn M., Heym, Kenneth M., Katz, Aaron J., Kelsh, Michael A., Sposto, Richard, Tu, Huakang, Tuglus, Catherine A., Verma, Anupam, Vinti, Luciana, Wilkes, Jennifer J., Zubarovskaja, Nathalya, Zugmaier, Gerhard, von Stackelberg, Arend, Sun, Weili
Julkaisussa Leukemia (2020)

Effect of Blinatumomab vs Chemotherapy on Event-Free Survival Among Children With High-risk First-Relapse B-Cell Acute Lymphoblastic Leukemia: A Randomized Clinical Trial

Tekijä Locatelli, Franco, Zugmaier, Gerhard, Rizzari, Carmelo, Morris, Joan D., Gruhn, Bernd, Klingebiel, Thomas, Parasole, Rosanna, Linderkamp, Christin, Flotho, Christian, Petit, Arnaud, Micalizzi, Concetta, Mergen, Noemi, Mohammad, Abeera, Kormany, William N., Eckert, Cornelia, Möricke, Anja, Sartor, Mary, Hrusak, Ondrej, Peters, Christina, Saha, Vaskar, Vinti, Luciana, von Stackelberg, Arend
Julkaisussa JAMA (2021)

Long non-coding RNAs defining major subtypes of B cell precursor acute lymphoblastic leukemia

Tekijä James, Alva Rani, Schroeder, Michael P., Neumann, Martin, Bastian, Lorenz, Eckert, Cornelia, Gökbuget, Nicola, Tanchez, Jutta Ortiz, Schlee, Cornelia, Isaakidis, Konstandina, Schwartz, Stefan, Burmeister, Thomas, von Stackelberg, Arend, Rieger, Michael A., Göllner, Stefanie, Horstman, Martin, Schrappe, Martin, Kirschner-Schwabe, Renate, Brüggemann, Monika, Müller-Tidow, Carsten, Serve, Hubert, Akalin, Altuna, Baldus, Claudia D.
Julkaisussa J Hematol Oncol (2019)

Pediatric T-cell lymphoblastic leukemia evolves into relapse by clonal selection, acquisition of mutations and promoter hypomethylation

Tekijä Kunz, Joachim B., Rausch, Tobias, Bandapalli, Obul R., Eilers, Juliane, Pechanska, Paulina, Schuessele, Stephanie, Assenov, Yassen, Stütz, Adrian M., Kirschner-Schwabe, Renate, Hof, Jana, Eckert, Cornelia, von Stackelberg, Arend, Schrappe, Martin, Stanulla, Martin, Koehler, Rolf, Avigad, Smadar, Elitzur, Sarah, Handgretinger, Rupert, Benes, Vladimir, Weischenfeldt, Joachim, Korbel, Jan O., Muckenthaler, Martina U., Kulozik, Andreas E.
Julkaisussa Haematologica (2015)

The activating STAT5B N642H mutation is a common abnormality in pediatric T-cell acute lymphoblastic leukemia and confers a higher risk of relapse

Tekijä Bandapalli, Obul R., Schuessele, Stephanie, Kunz, Joachim B., Rausch, Tobias, Stütz, Adrian M., Tal, Noa, Geron, Ifat, Gershman, Nava, Izraeli, Shai, Eilers, Juliane, Vaezipour, Nina, Kirschner-Schwabe, Renate, Hof, Jana, von Stackelberg, Arend, Schrappe, Martin, Stanulla, Martin, Zimmermann, Martin, Koehler, Rolf, Avigad, Smadar, Handgretinger, Rupert, Frismantas, Viktoras, Bourquin, Jean Pierre, Bornhauser, Beat, Korbel, Jan O., Muckenthaler, Martina U., Kulozik, Andreas E.
Julkaistu 2014

Risk assessment of relapse by lineage-specific monitoring of chimerism in children undergoing allogeneic stem cell transplantation for acute lymphoblastic leukemia

Tekijä Preuner, Sandra, Peters, Christina, Pötschger, Ulrike, Daxberger, Helga, Fritsch, Gerhard, Geyeregger, Rene, Schrauder, André, von Stackelberg, Arend, Schrappe, Martin, Bader, Peter, Ebell, Wolfram, Eckert, Cornelia, Lang, Peter, Sykora, Karl-Walter, Schrum, Johanna, Kremens, Bernhard, Ehlert, Karoline, Albert, Michael H., Meisel, Roland, Lawitschka, Anita, Mann, Georg, Panzer-Grümayer, Renate, Güngör, Tayfun, Holter, Wolfgang, Strahm, Brigitte, Gruhn, Bernd, Schulz, Ansgar, Woessmann, Wilhelm, Lion, Thomas
Julkaisussa Haematologica (2016)