Recent Advances in Transition-Metal-Free Late-Stage C-H and N-H Arylation of Heteroarenes Using Diaryliodonium Salts

per Besson, Thierry, Fruit, Corinne
Publicat a Pharmaceuticals (Basel) (2021)

Microwave-Assisted Sequential One-Pot Synthesis of 8-Substituted Pyrazolo[1,5-a][1,3,5]triazines

per Elie, Jonathan, Fruit, Corinne, Besson, Thierry
Publicat a Molecules (2021)

26th Annual GP2A Medicinal Chemistry Conference & 32nd Journées Franco-Belges de Pharmacochimie

per Dallemagne, Patrick, Rochais, Christophe, Marchand, Pascal, Besson, Thierry
Publicat a Pharmaceuticals (Basel) (2019)

Synthesis of Thiazolo[5,4-f]quinazolin-9(8H)-ones as Multi-Target Directed Ligands of Ser/Thr Kinases

per Hédou, Damien, Godeau, Julien, Loaëc, Nadège, Meijer, Laurent, Fruit, Corinne, Besson, Thierry
Publicat a Molecules (2016)

Synthesis of Bioactive 2-(Arylamino)thiazolo[5,4-f]-quinazolin-9-ones via the Hügershoff Reaction or Cu- Catalyzed Intramolecular C-S Bond Formation

per Hédou, Damien, Dubouilh-Benard, Carole, Loaëc, Nadège, Meijer, Laurent, Fruit, Corinne, Besson, Thierry
Publicat a Molecules (2016)

Microwave-Assisted Synthesis of Potential Bioactive Benzo-, Pyrido- or Pyrazino-thieno[3,2-d]pyrimidin-4-amine Analogs of MPC-6827

per Loidreau, Yvonnick, Nourrisson, Marie-Renée, Fruit, Corinne, Corbière, Cécile, Marchand, Pascal, Besson, Thierry
Publicat a Pharmaceuticals (Basel) (2020)

Demonstration of Green Solvent Performance on O,S,N-Heterocycles Synthesis: Metal-Free Click Chemistry and Buchwald—Hartwig Coupling

per Campos, Joana F., Cailler, Manon, Claudel, Remi, Prot, Benjamin, Besson, Thierry, Berteina-Raboin, Sabine
Publicat a Molecules (2021)

Exploring Kinase Inhibition Properties of 9H-pyrimido[5,4-b]- and [4,5-b]indol-4-amine Derivatives

per Loidreau, Yvonnick, Dubouilh-Benard, Carole, Nourrisson, Marie-Renée, Loaëc, Nadège, Meijer, Laurent, Besson, Thierry, Marchand, Pascal
Publicat a Pharmaceuticals (Basel) (2020)

Synthesis of 2-Mercapto-(2-Oxoindolin-3-Ylidene)Acetonitriles from 3-(4-Chloro-5H-1,2,3-Dithiazol-5-Ylidene)Indolin-2-ones

per Letribot, Boris, Delatouche, Régis, Rouillard, Hervé, Bonnet, Antoine, Chérouvrier, Jean-René, Domon, Lisianne, Besson, Thierry, Thiéry, Valérie
Publicat a Molecules (2018)

Biological Characterization of 8-Cyclopropyl-2-(pyridin-3-yl)thiazolo[5,4-f]quinazolin-9(8H)-one, a Promising Inhibitor of DYRK1A

per Fruit, Corinne, Couly, Florence, Bhansali, Rahul, Rammohan, Malini, Lindberg, Mattias F., Crispino, John D., Meijer, Laurent, Besson, Thierry
Publicat a Pharmaceuticals (Basel) (2019)

Design and Synthesis of Thiazolo[5,4-f]quinazolines as DYRK1A Inhibitors, Part I

per Foucourt, Alicia, Hédou, Damien, Dubouilh-Benard, Carole, Désiré, Laurent, Casagrande, Anne-Sophie, Leblond, Bertrand, Loäec, Nadège, Meijer, Laurent, Besson, Thierry
Publicat a Molecules (2014)

Design and Synthesis of Thiazolo[5,4-f]quinazolines as DYRK1A Inhibitors, Part II

per Foucourt, Alicia, Hédou, Damien, Dubouilh-Benard, Carole, Girard, Angélique, Taverne, Thierry, Casagrande, Anne-Sophie, Désiré, Laurent, Leblond, Bertrand, Besson, Thierry
Publicat a Molecules (2014)

Discovery of a Novel Broad-Spectrum Antifungal Agent Derived from Albaconazole

per Guillon, Rémi, Pagniez, Fabrice, Picot, Carine, Hédou, Damien, Tonnerre, Alain, Chosson, Elizabeth, Duflos, Muriel, Besson, Thierry, Logé, Cédric, Le Pape, Patrice
Publicat 2013

Development of Kinase Inhibitors via Metal-Catalyzed C–H Arylation of 8-Alkyl-thiazolo[5,4-f]-quinazolin-9-ones Designed by Fragment-Growing Studies

per Couly, Florence, Harari, Marine, Dubouilh-Benard, Carole, Bailly, Laetitia, Petit, Emilie, Diharce, Julien, Bonnet, Pascal, Meijer, Laurent, Fruit, Corinne, Besson, Thierry
Publicat a Molecules (2018)

DYRK1A controls the transition from proliferation to quiescence during lymphoid development by destabilizing Cyclin D3

per Thompson, Benjamin J., Bhansali, Rahul, Diebold, Lauren, Cook, Daniel E., Stolzenburg, Lindsay, Casagrande, Anne-Sophie, Besson, Thierry, Leblond, Bertrand, Désiré, Laurent, Malinge, Sébastien, Crispino, John D.
Publicat a J Exp Med (2015)

DYRK1A regulates B cell acute lymphoblastic leukemia through phosphorylation of FOXO1 and STAT3

per Bhansali, Rahul S., Rammohan, Malini, Lee, Paul, Laurent, Anouchka P., Wen, Qiang, Suraneni, Praveen, Yip, Bon Ham, Tsai, Yi-Chien, Jenni, Silvia, Bornhauser, Beat, Siret, Aurélie, Fruit, Corinne, Pacheco-Benichou, Alexandra, Harris, Ethan, Besson, Thierry, Thompson, Benjamin J., Goo, Young Ah, Hijiya, Nobuko, Vilenchik, Maria, Izraeli, Shai, Bourquin, Jean-Pierre, Malinge, Sébastien, Crispino, John D.
Publicat a J Clin Invest (2021)