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Mitochondria: gatekeepers of response to chemotherapy

Mitochondria are cellular organelles that regulate commitment and execution of apoptosis. The intrinsic apoptotic pathway culminates in the permeabilization of the mitochondrial outer membrane and dismantling of the cell. Apoptosis of cancer cells is a favorable outcome when administering chemothera...

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Bibliografiska uppgifter
Huvudupphovsmän: Sarosiek, Kristopher A., Chonghaile, Triona Ni, Letai, Anthony
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842421/
https://ncbi.nlm.nih.gov/pubmed/24060597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2013.08.003
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