Ganglioside GD2 identifies breast cancer stem cells and promotes tumorigenesis

Cancer stem cells (CSCs) are a small subpopulation of cancer cells that have increased resistance to conventional therapies and are capable of establishing metastasis. However, only a few biomarkers of CSCs have been identified. Here, we report that ganglioside GD2 (a glycosphingolipid) identifies a...

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Detalhes bibliográficos
Main Authors: Battula, Venkata Lokesh, Shi, Yuexi, Evans, Kurt W., Wang, Rui-Yu, Spaeth, Erika L., Jacamo, Rodrigo O., Guerra, Rudy, Sahin, Aysegul A., Marini, Frank C., Hortobagyi, Gabriel, Mani, Sendurai A., Andreeff, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591166/
https://ncbi.nlm.nih.gov/pubmed/22585577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI59735
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