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GD2 and GD3 synthase: novel drug targets for cancer therapy

Our recent study suggests that targeting GD3 synthase (also known as ST8SIA1)—the rate-limiting enzyme in biosynthesis of the breast cancer stem cell marker GD2—abrogates metastasis and depletes the cancer stem cell populations within a tumor, thus providing an effective therapeutic strategy against...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Sphyris, Nathalie, Sarkar, Tapasree Roy, Battula, Venkata L, Andreeff, Michael, Mani, Sendurai A
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905286/
https://ncbi.nlm.nih.gov/pubmed/27308452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23723556.2014.975068
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